| Player | Team | Action | Details | |
|---|---|---|---|---|
| Miguel Bleis | Supreme Clientele | ADD | to A | 1:29 pm, 6/6/22 |
| Jared Koenig | Bullet Club | ADD | to AAA | 12:57 pm, 6/6/22 |
| Spencer Steer | The Bluth Company | ADD | to AAA | 9:25 am, 6/6/22 |
| Kolten Wong | The Red Barons | ADD | to MLB | 5:48 am, 6/6/22 |
| Omar Narvaez | The Red Barons | ADD | to MLB | 5:47 am, 6/6/22 |
| Seranthony Dominguez | Chinballs | ADD | to MLB | 3:29 am, 6/6/22 |
| Jared Koenig | The Bluth Company | ADD | to AAA | 4:46 pm, 6/5/22 |
| Packy Naughton | Chinballs | ADD | to AAA | 12:20 pm, 6/5/22 |
| Spencer Steer | The Bluth Company | ADD | to AAA | 12:19 pm, 6/5/22 |
| Matt Swarmer | Monk's Café | ADD | to MLB | 12:18 pm, 6/5/22 |
| Andre Pallante | Monk's Café | ADD | to MLB | 12:18 pm, 6/5/22 |
| Jason Adam | Monk's Café | ADD | to MLB | 12:18 pm, 6/5/22 |
| Jon Berti | Bullet Club | ADD | to MLB | 8:27 am, 6/5/22 |
| Christian Vazquez | Undead Rabbits | ADD | to MLB | 9:53 pm, 6/4/22 |
| Seranthony Dominguez | Undead Rabbits | ADD | to AAA | 9:50 pm, 6/4/22 |
| Travis Swaggerty | Chinballs | ADD | to AAA | 8:45 pm, 6/4/22 |
| Bryce Ball | The Bluth Company | ADD | to AAA | 2:38 pm, 6/4/22 |
| Tucupita Marcano | The Bluth Company | ADD | to MLB | 2:09 pm, 6/4/22 |
| Matt Carpenter | Cowboys From Hell | ADD | to MLB | 12:42 pm, 6/4/22 |
| Rafael Ortega | Cowboys From Hell | ADD | to MLB | 12:42 pm, 6/4/22 |
| Ramon Urias | Bullet Club | ADD | to MLB | 2:29 pm, 6/3/22 |
| Logan O'Hoppe | The Bluth Company | ADD | to AA | 11:38 am, 6/3/22 |
| Colt Keith | The Bluth Company | ADD | to AAA | 9:17 am, 6/3/22 |
| David Peralta | Jon Voight's Car | ADD | to MLB | 7:19 pm, 6/2/22 |
| Dallas Keuchel | Bridge Four | ADD | to MLB | 12:30 pm, 6/2/22 |