| Player | Team | Action | Details | |
|---|---|---|---|---|
| Miguel Andujar | Monk's Café | ADD | to MLB | 7:20 am, 5/26/22 |
| Harold Ramirez | Chinballs | ADD | to MLB | 4:30 am, 5/26/22 |
| Jonathan Schoop | Geckos | ADD | to MLB | 7:03 pm, 5/25/22 |
| Gio Urshela | The Red Barons | ADD | to MLB | 11:44 am, 5/25/22 |
| A.J. Minter | Ye Olde Tom Toolshed | ADD | to MLB | 10:54 am, 5/25/22 |
| Thomas Szapucki | Chinballs | ADD | to MLB | 3:42 am, 5/25/22 |
| Kyle Freeland | Chinballs | ADD | to MLB | 3:38 am, 5/25/22 |
| Ethan Hankins | Chinballs | ADD | to MLB | 3:37 am, 5/25/22 |
| Matt Barnes | Chinballs | ADD | to MLB | 2:27 am, 5/25/22 |
| Alec Burleson | The Bluth Company | ADD | to AAA | 8:47 am, 5/24/22 |
| Josh Winckowski | Undead Rabbits | ADD | to AA | 12:55 am, 5/24/22 |
| Grant McCray | The Bluth Company | ADD | to AA | 2:14 pm, 5/23/22 |
| Frank Schwindel | Geckos | ADD | to MLB | 2:12 pm, 5/23/22 |
| Art Warren | Geckos | ADD | to MLB | 2:11 pm, 5/23/22 |
| Colt Keith | The Bluth Company | ADD | to A | 9:11 am, 5/23/22 |
| Matthew Strahm | The Red Barons | ADD | to MLB | 6:19 am, 5/23/22 |
| Emmanuel Rivera | Chinballs | ADD | to MLB | 3:37 am, 5/23/22 |
| Luis Rengifo | Bullet Club | ADD | to MLB | 7:47 pm, 5/22/22 |
| Reese Olson | The Bluth Company | ADD | to AA | 9:17 pm, 5/21/22 |
| Josh Winckowski | The Bluth Company | ADD | to AAA | 4:13 pm, 5/21/22 |
| Reese Olson | The Bluth Company | ADD | to AA | 8:45 pm, 5/20/22 |
| Bobby Dalbec | Cowboys From Hell | ADD | to MLB | 5:18 pm, 5/20/22 |
| Kole Calhoun | Cowboys From Hell | ADD | to MLB | 5:18 pm, 5/20/22 |
| Mason Montgomery | Cowboys From Hell | ADD | to AA | 5:03 pm, 5/20/22 |
| Wilmer Flores | The Bluth Company | ADD | to A | 5:02 pm, 5/20/22 |