| Player | Team | Action | Details | |
|---|---|---|---|---|
| Yosver Zulueta | The Bluth Company | ADD | to AAA | 3:59 pm, 4/29/22 |
| Martin Perez | The Bluth Company | ADD | to MLB | 11:58 am, 4/29/22 |
| Erik Swanson | The Bluth Company | ADD | to MLB | 11:53 am, 4/29/22 |
| Esteury Ruiz | Ye Olde Tom Toolshed | ADD | to AA | 6:36 pm, 4/28/22 |
| Brian Anderson | Geckos | ADD | to MLB | 3:50 pm, 4/28/22 |
| Odubel Herrera | Geckos | ADD | to MLB | 3:49 pm, 4/28/22 |
| Paul Sewald | The Bluth Company | ADD | to MLB | 2:07 pm, 4/28/22 |
| Nick Nastrini | The Bluth Company | ADD | to A | 2:07 pm, 4/28/22 |
| Brock Burke | The Bluth Company | ADD | to AAA | 2:04 pm, 4/28/22 |
| Jorge Alfaro | Monk's Café | ADD | to MLB | 11:00 am, 4/28/22 |
| Calvin Mitchell | Bullet Club | ADD | to MLB | 10:38 am, 4/28/22 |
| Jake Burger | Geckos | ADD | to AAA | 3:06 pm, 4/27/22 |
| Alex Binelas | Chinballs | ADD | to A | 2:38 pm, 4/27/22 |
| Moises Gomez | Shaolin Schmeckles | ADD | to AAA | 9:51 am, 4/27/22 |
| Wilmer Flores | Bullet Club | ADD | to MLB | 8:52 am, 4/27/22 |
| Marco Raya | The Bluth Company | ADD | to A | 8:09 am, 4/27/22 |
| Craig Stammen | Nixon's Nasty Ninjas | ADD | to MLB | 9:36 pm, 4/26/22 |
| Drew Smith | Geckos | ADD | to MLB | 5:28 pm, 4/26/22 |
| Miguel Andujar | Cowboys From Hell | ADD | to MLB | 5:26 pm, 4/26/22 |
| Andrew Abbott | Geckos | ADD | to AA | 2:10 pm, 4/26/22 |
| Devin Williams | The Bluth Company | ADD | to MLB | 1:02 pm, 4/26/22 |
| Dany Jimenez | Shaolin Schmeckles | ADD | to MLB | 11:32 am, 4/26/22 |
| Michael Chavis | Bullet Club | ADD | to MLB | 11:26 am, 4/26/22 |
| Chris Stratton | Shaolin Schmeckles | ADD | to MLB | 11:09 am, 4/26/22 |
| Michael King | The Bluth Company | ADD | to MLB | 11:01 am, 4/26/22 |