| Player | Team | Action | Details | |
|---|---|---|---|---|
| Clayton Beeter | The Bluth Company | ADD | to AA | 11:36 pm, 8/23/21 |
| Jake McCarthy | Ye Olde Tom Toolshed | ADD | to AAA | 4:41 pm, 8/23/21 |
| Adam Ottavino | Shaolin Schmeckles | ADD | to MLB | 4:39 pm, 8/23/21 |
| Humberto Mejia | Shaolin Schmeckles | ADD | to MLB | 12:21 pm, 8/23/21 |
| Paul Blackburn | Shaolin Schmeckles | ADD | to MLB | 12:21 pm, 8/23/21 |
| Victor Gonzalez | Shaolin Schmeckles | ADD | to MLB | 3:29 pm, 8/22/21 |
| Phil Bickford | Shaolin Schmeckles | ADD | to MLB | 3:15 pm, 8/22/21 |
| Jake Diekman | Kimble's Kids | ADD | to MLB | 12:59 pm, 8/22/21 |
| Justin Upton | Kimble's Kids | ADD | to MLB | 12:58 pm, 8/22/21 |
| Miguel Cabrera | Kimble's Kids | ADD | to MLB | 12:58 pm, 8/22/21 |
| Odubel Herrera | Cowboys From Hell | ADD | to MLB | 10:34 am, 8/22/21 |
| Drey Jameson | Cowboys From Hell | ADD | to AA | 8:13 am, 8/21/21 |
| Dillon Peters | Shaolin Schmeckles | ADD | to MLB | 3:12 am, 8/21/21 |
| Yasel Antuna | The Red Barons | ADD | to AA | 11:03 pm, 8/20/21 |
| Lars Nootbaar | Cowboys From Hell | ADD | to MLB | 9:10 pm, 8/20/21 |
| Dillon Peters | Shaolin Schmeckles | ADD | to MLB | 12:14 pm, 8/20/21 |
| Curtis Mead | Purple Cobras | ADD | to A | 12:03 pm, 8/20/21 |
| Cesar Hernandez | Ye Olde Tom Toolshed | ADD | to MLB | 9:42 am, 8/20/21 |
| Ezequiel Tovar | Purple Cobras | ADD | to A | 9:26 am, 8/20/21 |
| Andrew Velazquez | Shaolin Schmeckles | ADD | to MLB | 5:54 pm, 8/19/21 |
| Yohel Pozo | Ye Olde Tom Toolshed | ADD | to MLB | 2:25 pm, 8/19/21 |
| Adam Oller | Purple Cobras | ADD | to AAA | 2:21 pm, 8/19/21 |
| Mitchell White | The Bluth Company | ADD | to AAA | 8:42 am, 8/19/21 |
| Jacob Brentz | Shaolin Schmeckles | ADD | to MLB | 3:23 am, 8/19/21 |
| Kevin Smith | The Bluth Company | ADD | to AAA | 11:55 pm, 8/17/21 |