| Player | Team | Action | Details | |
|---|---|---|---|---|
| Tim Adleman | Purple Cobras | ADD | to MLB | 11:16 pm, 4/21/17 |
| Ryan Mountcastle | The Bluth Company | ADD | to A | 10:53 pm, 4/21/17 |
| Jorge Bonifacio | The Bluth Company | ADD | to AAA | 5:57 pm, 4/21/17 |
| Nick Ahmed | Bridge Four | ADD | to MLB | 5:40 pm, 4/21/17 |
| Luis Escobar | Supreme Clientele | ADD | to AA | 2:51 pm, 4/21/17 |
| Marcus Wilson | Supreme Clientele | ADD | to AA | 2:21 pm, 4/21/17 |
| Jered Weaver | Purple Cobras | ADD | to MLB | 1:05 pm, 4/21/17 |
| Jacob Barnes | Purple Cobras | ADD | to MLB | 12:52 pm, 4/21/17 |
| Josh Tomlin | Scranton Yankees | ADD | to MLB | 9:30 am, 4/21/17 |
| Vladimir Gutierrez | The Bluth Company | ADD | to A | 8:38 am, 4/21/17 |
| Zack Burdi | Supreme Clientele | ADD | to AA | 12:48 am, 4/21/17 |
| Nick Pivetta | Purple Cobras | ADD | to AAA | 11:42 pm, 4/20/17 |
| Jett Bandy | Purple Cobras | ADD | to MLB | 11:35 pm, 4/20/17 |
| Monte Harrison | The Bluth Company | ADD | to A | 11:35 pm, 4/20/17 |
| Vladimir Gutierrez | The Bluth Company | ADD | to A | 9:34 pm, 4/20/17 |
| Wade Miley | The Bluth Company | ADD | to MLB | 9:32 pm, 4/20/17 |
| Vladimir Gutierrez | The Bluth Company | ADD | to A | 9:01 pm, 4/20/17 |
| Hyun-Soo Kim | The Red Barons | ADD | to MLB | 5:55 pm, 4/20/17 |
| Daniel Brito | Chinballs | ADD | to AAA | 4:56 pm, 4/20/17 |
| Lamonte Wade | Chinballs | ADD | to AAA | 2:53 pm, 4/20/17 |
| Cody Sedlock | Purple Cobras | ADD | to AA | 2:19 pm, 4/20/17 |
| Yunel Escobar | Purple Cobras | ADD | to MLB | 1:45 pm, 4/20/17 |
| Aristides Aquino | The Bluth Company | ADD | to AAA | 1:05 pm, 4/20/17 |
| Ross Stripling | Banana Hammock | ADD | to MLB | 1:03 pm, 4/20/17 |
| Nick Pivetta | The Bluth Company | ADD | to AAA | 12:48 pm, 4/20/17 |