| Player | Team | Action | Details | |
|---|---|---|---|---|
| Logan S. Allen | Cowboys From Hell | ADD | to A | 1:52 pm, 5/9/16 |
| Lamonte Wade | Young Tommy Toolsheds | ADD | to A | 10:19 am, 5/9/16 |
| Michael Brantley | Young Tommy Toolsheds | ADD | to MLB | 10:16 am, 5/9/16 |
| Pedro Fernandez | Scranton Yankees | ADD | to A | 8:10 am, 5/9/16 |
| Miguel Gonzalez | Dead Rabbits | ADD | to MLB | 11:38 pm, 5/8/16 |
| David Hernandez | Dead Rabbits | ADD | to MLB | 11:37 pm, 5/8/16 |
| Justin Bour | Supreme Clientele | ADD | to MLB | 10:11 pm, 5/8/16 |
| Tony Cingrani | Supreme Clientele | ADD | to MLB | 10:10 pm, 5/8/16 |
| Justin Nicolino | Scranton Yankees | ADD | to AAA | 8:19 pm, 5/8/16 |
| Daniel Mengden | The Bluth Company | ADD | to AAA | 5:28 pm, 5/8/16 |
| Jeremy Hazelbaker | Purple Cobras | ADD | to MLB | 4:57 pm, 5/8/16 |
| Joey Rickard | Purple Cobras | ADD | to MLB | 4:47 pm, 5/8/16 |
| Melvin Upton Jr. | Kimble's Kids | ADD | to MLB | 3:02 pm, 5/8/16 |
| Harold Ramirez | Scranton Yankees | ADD | to A | 12:44 pm, 5/8/16 |
| Andrew Bailey | Scranton Yankees | ADD | to MLB | 10:47 pm, 5/7/16 |
| Jorge Lopez | Scranton Yankees | ADD | to AA | 10:44 pm, 5/7/16 |
| Ryan Zimmerman | Scranton Yankees | ADD | to MLB | 10:43 pm, 5/7/16 |
| Matt Adams | Scranton Yankees | ADD | to MLB | 10:42 pm, 5/7/16 |
| Cody Anderson | The Red Barons | ADD | to AAA | 1:05 pm, 5/7/16 |
| Jose Ramirez | The Red Barons | ADD | to MLB | 12:16 pm, 5/7/16 |
| Steve Pearce | Purple Cobras | ADD | to MLB | 1:32 am, 5/7/16 |
| Brian Johnson | Supreme Clientele | ADD | to MLB | 9:54 pm, 5/6/16 |
| Matt Andriese | Geckos | ADD | to MLB | 8:15 pm, 5/6/16 |
| CC Sabathia | Dead Rabbits | ADD | to MLB | 3:18 pm, 5/6/16 |
| Rio Ruiz | Banana Hammock | ADD | to AA | 2:25 pm, 5/6/16 |