| Player | Team | Action | Details | |
|---|---|---|---|---|
| Randal Grichuk | Scranton Yankees | DROP | to FA | 9:11 am, 9/24/22 |
| Jackson (Clint) Frazier | Scranton Yankees | DROP | to FA | 9:10 am, 9/24/22 |
| Oswaldo Cabrera | Scranton Yankees | DROP | to FA | 9:08 am, 9/24/22 |
| Josue De Paula | The Bluth Company | DROP | to FA | 1:59 pm, 9/23/22 |
| David Festa | The Bluth Company | DROP | to FA | 1:25 pm, 9/23/22 |
| Lane Thomas | Bullet Club | DROP | to FA | 9:20 am, 9/23/22 |
| Aristides Aquino | Bullet Club | DROP | to FA | 9:20 am, 9/23/22 |
| Gio Urshela | Bullet Club | DROP | to FA | 9:20 am, 9/23/22 |
| Jose Suarez | The Bluth Company | DROP | to FA | 10:18 am, 9/20/22 |
| Dominic Smith | Shaolin Schmeckles | DROP | to FA | 7:31 pm, 9/19/22 |
| David Peterson | Shaolin Schmeckles | DROP | to FA | 6:17 pm, 9/19/22 |
| Jose Siri | Shaolin Schmeckles | DROP | to FA | 6:17 pm, 9/19/22 |
| Joey Wendle | Shaolin Schmeckles | DROP | to FA | 6:17 pm, 9/19/22 |
| Glenn Otto | Shaolin Schmeckles | DROP | to FA | 6:17 pm, 9/19/22 |
| David Festa | The Bluth Company | DROP | to FA | 10:00 am, 9/19/22 |
| Josh Winder | The Red Barons | DROP | to FA | 9:28 am, 9/19/22 |
| Corey Kluber | Bullet Club | DROP | to FA | 2:34 pm, 9/18/22 |
| Giovanny Gallegos | Supreme Clientele | DROP | to FA | 2:14 pm, 9/18/22 |
| Evan Phillips | Supreme Clientele | DROP | to FA | 2:14 pm, 9/18/22 |
| Tommy Henry | Supreme Clientele | DROP | to FA | 2:14 pm, 9/18/22 |
| Myles Straw | The Red Barons | DROP | to FA | 3:25 am, 9/18/22 |
| Louie Varland | The Bluth Company | DROP | to FA | 6:46 pm, 9/17/22 |
| Tony Kemp | Cowboys From Hell | DROP | to FA | 9:38 am, 9/17/22 |
| Justin Dunn | Cowboys From Hell | DROP | to FA | 9:37 am, 9/17/22 |
| Dakota Hudson | The Red Barons | DROP | to FA | 8:39 am, 9/17/22 |