| Player | Team | Action | Details | |
|---|---|---|---|---|
| Trey Cabbage | Monk's Café | DROP | to FA | 10:00 am, 7/6/22 |
| Joshua Baez | The Red Barons | DROP | to FA | 9:38 pm, 7/5/22 |
| Andry Lara | The Red Barons | DROP | to FA | 1:20 pm, 7/5/22 |
| Colt Keith | The Bluth Company | DROP | to FA | 11:17 am, 7/5/22 |
| Yadier Molina | Jon Voight's Car | DROP | to FA | 10:43 am, 7/5/22 |
| Gleider Figuereo | The Red Barons | DROP | to FA | 10:41 am, 7/5/22 |
| Adrian Houser | Supreme Clientele | DROP | to FA | 8:31 am, 7/5/22 |
| Zack Thompson | Chinballs | DROP | to FA | 11:29 pm, 7/4/22 |
| Jace Peterson | Kimble's Kids | DROP | to FA | 1:41 pm, 7/4/22 |
| Joey Wendle | Chinballs | DROP | to FA | 5:03 am, 7/4/22 |
| Dan Vogelbach | Chinballs | DROP | to FA | 11:34 pm, 7/3/22 |
| Orlando Arcia | Monk's Café | DROP | to FA | 7:01 am, 7/3/22 |
| Lane Thomas | Cowboys From Hell | DROP | to FA | 1:12 pm, 7/2/22 |
| Heriberto Hernandez | Supreme Clientele | DROP | to FA | 9:46 am, 7/2/22 |
| Kole Calhoun | Chinballs | DROP | to FA | 12:26 pm, 7/1/22 |
| Jason Alexander | Geckos | DROP | to FA | 10:35 am, 7/1/22 |
| Lamonte Wade | The Red Barons | DROP | to FA | 9:33 am, 7/1/22 |
| Jonathan Hernandez | Chinballs | DROP | to FA | 3:18 am, 7/1/22 |
| Jake Burger | Chinballs | DROP | to FA | 3:18 am, 7/1/22 |
| Hao Yu Lee | The Red Barons | DROP | to FA | 9:58 pm, 6/30/22 |
| Jon Heasley | Bullet Club | DROP | to FA | 10:28 am, 6/30/22 |
| Enrique Hernandez | Chinballs | DROP | to FA | 12:08 am, 6/30/22 |
| Randy Rodriguez | The Red Barons | DROP | to FA | 1:18 pm, 6/29/22 |
| Mason Denaburg | The Red Barons | DROP | to FA | 12:53 pm, 6/29/22 |
| Mark Canha | The Red Barons | DROP | to FA | 8:35 am, 6/29/22 |