| Player | Team | Action | Details | |
|---|---|---|---|---|
| Chris Archer | Supreme Clientele | DROP | to FA | 3:05 pm, 5/17/22 |
| Joe Perez | Undead Rabbits | DROP | to FA | 8:29 am, 5/17/22 |
| Edwin Rios | Chinballs | DROP | to FA | 7:04 am, 5/17/22 |
| Milan Tolentino | The Bluth Company | DROP | to FA | 5:11 pm, 5/16/22 |
| Griffin Jax | Cowboys From Hell | DROP | to FA | 2:49 pm, 5/16/22 |
| Paul DeJong | Cowboys From Hell | DROP | to FA | 2:48 pm, 5/16/22 |
| Tony Santillan | Undead Rabbits | DROP | to FA | 11:30 am, 5/16/22 |
| Jose Iglesias | The Bluth Company | DROP | to FA | 11:29 am, 5/16/22 |
| Griff McGarry | The Bluth Company | DROP | to FA | 9:43 am, 5/16/22 |
| Devin Smeltzer | Bullet Club | DROP | to FA | 8:23 am, 5/16/22 |
| Michael Grove | The Bluth Company | DROP | to FA | 9:52 pm, 5/15/22 |
| Anthony Garcia | Monk's Café | DROP | to FA | 8:49 pm, 5/15/22 |
| Christian Encarnacion-Strand | Chinballs | DROP | to FA | 8:22 pm, 5/15/22 |
| Cesar Hernandez | Geckos | DROP | to FA | 2:05 pm, 5/15/22 |
| Joshua Mears | Geckos | DROP | to FA | 1:44 pm, 5/15/22 |
| Alec Marsh | The Red Barons | DROP | to FA | 11:19 am, 5/14/22 |
| Jordyn Adams | Bullet Club | DROP | to FA | 9:34 am, 5/14/22 |
| Bobby Dalbec | Bullet Club | DROP | to FA | 9:33 am, 5/14/22 |
| Dinelson Lamet | Cowboys From Hell | DROP | to FA | 6:43 pm, 5/13/22 |
| Matt Barnes | Cowboys From Hell | DROP | to FA | 6:43 pm, 5/13/22 |
| Robbie Grossman | Cowboys From Hell | DROP | to FA | 6:43 pm, 5/13/22 |
| Brandon Crawford | The Bluth Company | DROP | to FA | 11:12 am, 5/13/22 |
| Griff McGarry | The Bluth Company | DROP | to FA | 10:27 am, 5/13/22 |
| Gabriel Arias | The Red Barons | DROP | to FA | 9:50 pm, 5/12/22 |
| Adam Duvall | Shaolin Schmeckles | DROP | to FA | 4:04 pm, 5/12/22 |