| Player | Team | Action | Details | |
|---|---|---|---|---|
| Will Crowe | The Red Barons | DROP | to FA | 4:58 pm, 7/22/21 |
| Gilberto Celestino | Shaolin Schmeckles | DROP | to FA | 4:02 pm, 7/22/21 |
| Garrett Richards | Supreme Clientele | DROP | to FA | 12:58 pm, 7/22/21 |
| Jeff Hoffman | Supreme Clientele | DROP | to FA | 10:59 am, 7/22/21 |
| Starlin Castro | Bullet Club | DROP | to FA | 8:29 am, 7/22/21 |
| Masyn Winn | The Bluth Company | DROP | to FA | 12:12 am, 7/22/21 |
| Eury Perez | The Bluth Company | DROP | to FA | 11:48 pm, 7/21/21 |
| Phil Bickford | Undead Rabbits | DROP | to FA | 4:57 pm, 7/21/21 |
| Seth Lugo | Chinballs | DROP | to FA | 1:06 pm, 7/21/21 |
| Taj Bradley | The Bluth Company | DROP | to FA | 11:52 pm, 7/20/21 |
| Abraham Toro | Cowboys From Hell | DROP | to FA | 6:27 pm, 7/20/21 |
| Yonathan Daza | Cowboys From Hell | DROP | to FA | 6:27 pm, 7/20/21 |
| Kyle Farmer | Shaolin Schmeckles | DROP | to FA | 5:52 pm, 7/20/21 |
| Alexfri Planez | Ye Olde Tom Toolshed | DROP | to FA | 3:45 pm, 7/20/21 |
| Paolo Espino | Ye Olde Tom Toolshed | DROP | to FA | 3:44 pm, 7/20/21 |
| Kole Calhoun | The Bluth Company | DROP | to FA | 6:14 am, 7/20/21 |
| Vladimir Gutierrez | Purple Cobras | DROP | to FA | 10:33 pm, 7/19/21 |
| Wilmer Flores | Purple Cobras | DROP | to FA | 5:42 pm, 7/19/21 |
| Taylor Walls | The Bluth Company | DROP | to FA | 2:27 pm, 7/19/21 |
| Rich Hill | The Bluth Company | DROP | to FA | 2:01 pm, 7/19/21 |
| Kole Calhoun | The Bluth Company | DROP | to FA | 2:00 pm, 7/19/21 |
| Jake Woodford | Chinballs | DROP | to FA | 10:28 am, 7/19/21 |
| David Dahl | Chinballs | DROP | to FA | 9:52 am, 7/19/21 |
| Harold Ramirez | Purple Cobras | DROP | to FA | 8:13 am, 7/19/21 |
| Miguel Rojas | Purple Cobras | DROP | to FA | 7:31 pm, 7/18/21 |