| Player | Team | Action | Details | |
|---|---|---|---|---|
| Danny Duffy | Supreme Clientele | DROP | to FA | 6:14 pm, 3/21/21 |
| Cole Wilcox | Supreme Clientele | DROP | to FA | 6:11 pm, 3/21/21 |
| Chris Flexen | Supreme Clientele | DROP | to FA | 6:11 pm, 3/21/21 |
| Jon Lester | Supreme Clientele | DROP | to FA | 6:10 pm, 3/21/21 |
| Joe Ryan | Supreme Clientele | DROP | to FA | 6:01 pm, 3/21/21 |
| Josh Staumont | Supreme Clientele | DROP | to FA | 3:47 pm, 3/21/21 |
| Michael Grove | Chinballs | DROP | to FA | 5:56 pm, 3/18/21 |
| Blaze Jordan | Undead Rabbits | DROP | to FA | 12:49 am, 3/18/21 |
| Carter Kieboom | Undead Rabbits | DROP | to FA | 12:46 am, 3/18/21 |
| Garrett Cooper | Undead Rabbits | DROP | to FA | 12:39 am, 3/18/21 |
| Luis Oviedo | Chinballs | DROP | to FA | 10:47 am, 3/16/21 |
| Anthony Kay | Scranton Yankees | DROP | to FA | 10:42 am, 3/16/21 |
| Aaron Schunk | Purple Cobras | DROP | to FA | 9:41 am, 3/16/21 |
| Aaron Bummer | Scranton Yankees | DROP | to FA | 1:56 pm, 2/15/21 |
| Jeff Hoffman | Kimble's Kids | DROP | to FA | 10:11 am, 2/15/21 |
| Grant Holmes | Kimble's Kids | DROP | to FA | 10:04 am, 2/15/21 |
| Miguel Cabrera | Kimble's Kids | DROP | to FA | 9:49 am, 2/15/21 |
| Franklin Barreto | Jon Voight's Car | DROP | to FA | 9:49 am, 2/15/21 |
| Keoni Cavaco | Jon Voight's Car | DROP | to FA | 9:48 am, 2/15/21 |
| Tyler Beede | Jon Voight's Car | DROP | to FA | 9:48 am, 2/15/21 |
| Jackie Bradley Jr | Jon Voight's Car | DROP | to FA | 9:48 am, 2/15/21 |
| Roansy Contreras | Jon Voight's Car | DROP | to FA | 9:48 am, 2/15/21 |
| Yerry Rodriguez | Jon Voight's Car | DROP | to FA | 9:48 am, 2/15/21 |
| Brandon Workman | Jon Voight's Car | DROP | to FA | 9:47 am, 2/15/21 |
| Corey Ray | Jon Voight's Car | DROP | to FA | 9:47 am, 2/15/21 |