| Player | Team | Action | Details | |
|---|---|---|---|---|
| Lewis Brinson | Bullet Club | DROP | to FA | 2:12 am, 2/14/21 |
| Starlin Castro | Bullet Club | DROP | to FA | 2:12 am, 2/14/21 |
| Yandy Diaz | Bullet Club | DROP | to FA | 2:12 am, 2/14/21 |
| Juan Pablo Martinez | Cowboys From Hell | DROP | to FA | 10:17 pm, 2/13/21 |
| Brennan Malone | Chinballs | DROP | to FA | 9:43 pm, 2/13/21 |
| Vincent Velasquez | Supreme Clientele | DROP | to FA | 4:38 pm, 2/13/21 |
| Aaron Sanchez | Supreme Clientele | DROP | to FA | 4:38 pm, 2/13/21 |
| Scott Kingery | Supreme Clientele | DROP | to FA | 4:38 pm, 2/13/21 |
| Luis Frias | Purple Cobras | DROP | to FA | 1:28 pm, 2/13/21 |
| Seth Lugo | Chinballs | DROP | to FA | 12:35 pm, 2/13/21 |
| Danny Santana | Bullet Club | DROP | to FA | 7:17 pm, 2/12/21 |
| Ryan Braun | Bullet Club | DROP | to FA | 7:17 pm, 2/12/21 |
| Daniel Poncedeleon | Bullet Club | DROP | to FA | 7:17 pm, 2/12/21 |
| Adam Eaton | Cowboys From Hell | DROP | to FA | 3:42 pm, 2/12/21 |
| Yu Chang | Cowboys From Hell | DROP | to FA | 3:40 pm, 2/12/21 |
| Jeff Samardzija | Cowboys From Hell | DROP | to FA | 3:39 pm, 2/12/21 |
| Huascar Ynoa | Cowboys From Hell | DROP | to FA | 3:39 pm, 2/12/21 |
| Jeremy Jeffress | Cowboys From Hell | DROP | to FA | 3:36 pm, 2/12/21 |
| Joey Wentz | Cowboys From Hell | DROP | to FA | 3:36 pm, 2/12/21 |
| Jurickson Profar | Cowboys From Hell | DROP | to FA | 3:36 pm, 2/12/21 |
| Paredes Enoli | Shaolin Schmeckles | DROP | to FA | 12:51 pm, 2/12/21 |
| Ken Giles | Shaolin Schmeckles | DROP | to FA | 12:49 pm, 2/12/21 |
| Jairo Solis | Shaolin Schmeckles | DROP | to FA | 12:46 pm, 2/12/21 |
| Rafael Dolis | Shaolin Schmeckles | DROP | to FA | 10:59 pm, 2/11/21 |
| Jake Junis | Shaolin Schmeckles | DROP | to FA | 10:55 pm, 2/11/21 |