| Player | Team | Action | Details | |
|---|---|---|---|---|
| Sergio Romo | Supreme Clientele | DROP | to FA | 11:32 am, 10/12/16 |
| Jordan Stephens | The Bluth Company | DROP | to FA | 8:39 am, 10/11/16 |
| Jordan Hicks | The Bluth Company | DROP | to FA | 8:36 am, 10/11/16 |
| Cesar Hernandez | Supreme Clientele | DROP | to FA | 6:45 pm, 10/10/16 |
| Hunter Strickland | The Red Barons | DROP | to FA | 5:07 pm, 10/7/16 |
| Kyle Gibson | The Red Barons | DROP | to FA | 5:06 pm, 10/7/16 |
| Cody Ponce | The Red Barons | DROP | to FA | 4:52 pm, 10/7/16 |
| Jered Weaver | Scranton Yankees | DROP | to FA | 6:42 pm, 10/6/16 |
| Chad Bettis | Scranton Yankees | DROP | to FA | 6:41 pm, 10/6/16 |
| Jed Bradley | Scranton Yankees | DROP | to FA | 6:40 pm, 10/6/16 |
| Ross Detwiler | Scranton Yankees | DROP | to FA | 6:40 pm, 10/6/16 |
| Matt Garza | Supreme Clientele | DROP | to FA | 7:31 pm, 10/3/16 |
| Wily Peralta | Supreme Clientele | DROP | to FA | 6:31 pm, 10/3/16 |
| Marwin Gonzalez | Supreme Clientele | DROP | to FA | 6:31 pm, 10/3/16 |
| Kevin Siegrist | Purple Cobras | DROP | to FA | 8:11 pm, 10/2/16 |
| Mac Williamson | Dead Rabbits | DROP | to FA | 7:09 pm, 10/1/16 |
| Whit Merrifield | Purple Cobras | DROP | to FA | 8:11 am, 10/1/16 |
| Koji Uehara | Cowboys From Hell | DROP | to FA | 4:37 pm, 9/29/16 |
| Alcides Escobar | Cowboys From Hell | DROP | to FA | 4:35 pm, 9/29/16 |
| Freddy Galvis | Purple Cobras | DROP | to FA | 9:11 am, 9/29/16 |
| Michael Saunders | The Bluth Company | DROP | to FA | 3:06 am, 9/26/16 |
| Matt Olson | The Bluth Company | DROP | to FA | 3:05 am, 9/26/16 |
| Ross Stripling | Purple Cobras | DROP | to FA | 10:14 pm, 9/25/16 |
| John Gant | Purple Cobras | DROP | to FA | 10:14 pm, 9/25/16 |
| Freddy Galvis | Purple Cobras | DROP | to FA | 10:14 pm, 9/25/16 |