| Player | Team | Action | Details | |
|---|---|---|---|---|
| Ryan Vogelsong | Supreme Clientele | DROP | to FA | 10:19 am, 9/10/16 |
| David Freese | Bridge Four | DROP | to FA | 10:18 am, 9/10/16 |
| Jordy Mercer | Bridge Four | DROP | to FA | 10:17 am, 9/10/16 |
| Jarrod Dyson | Purple Cobras | DROP | to FA | 8:54 am, 9/10/16 |
| Nick Hundley | Purple Cobras | DROP | to FA | 8:49 am, 9/10/16 |
| Chase Anderson | Geckos | DROP | to FA | 8:43 am, 9/10/16 |
| Doug Fister | Geckos | DROP | to FA | 8:40 am, 9/10/16 |
| Asdrubal Cabrera | Geckos | DROP | to FA | 8:38 am, 9/10/16 |
| A.J. Schugel | Geckos | DROP | to FA | 8:38 am, 9/10/16 |
| Nick Wittgren | Geckos | DROP | to FA | 8:38 am, 9/10/16 |
| Cesar Hernandez | Purple Cobras | DROP | to FA | 12:08 am, 9/10/16 |
| Chris Taylor | Cowboys From Hell | DROP | to FA | 8:42 pm, 9/9/16 |
| Fernando Salas | Cowboys From Hell | DROP | to FA | 8:42 pm, 9/9/16 |
| J.J. Hardy | Cowboys From Hell | DROP | to FA | 8:41 pm, 9/9/16 |
| James McCann | Cowboys From Hell | DROP | to FA | 8:41 pm, 9/9/16 |
| Sal Romano | Geckos | DROP | to FA | 7:55 pm, 9/9/16 |
| Mark Reynolds | Nixon's Nasty Ninjas | DROP | to FA | 3:29 pm, 9/9/16 |
| Seth Smith | The Bluth Company | DROP | to FA | 1:04 pm, 9/9/16 |
| Dillon Gee | Supreme Clientele | DROP | to FA | 10:29 am, 9/9/16 |
| Justin Bour | Supreme Clientele | DROP | to FA | 10:29 am, 9/9/16 |
| Gerardo Parra | Supreme Clientele | DROP | to FA | 10:27 am, 9/9/16 |
| Logan Morrison | Purple Cobras | DROP | to FA | 12:07 am, 9/9/16 |
| Edwin Rios | Chinballs | DROP | to FA | 8:35 pm, 9/8/16 |
| Will Harris | Kimble's Kids | DROP | to FA | 7:02 pm, 9/8/16 |
| Andrew Susac | The Bluth Company | DROP | to FA | 12:08 pm, 9/8/16 |