| Player | Team | Action | Details | |
|---|---|---|---|---|
| Hunter Strickland | Nixon's Nasty Ninjas | DROP | to FA | 11:46 am, 8/8/16 |
| Jonathan Papelbon | The Red Barons | DROP | to FA | 11:30 am, 8/8/16 |
| Sergio Romo | Nixon's Nasty Ninjas | DROP | to FA | 10:35 am, 8/8/16 |
| Manny Banuelos | Nixon's Nasty Ninjas | DROP | to FA | 10:34 am, 8/8/16 |
| Tyrell Jenkins | Supreme Clientele | DROP | to FA | 9:14 am, 8/8/16 |
| Keone Kela | Supreme Clientele | DROP | to FA | 9:12 am, 8/8/16 |
| Steven Brault | Purple Cobras | DROP | to FA | 9:33 pm, 8/7/16 |
| Chad Green | Purple Cobras | DROP | to FA | 7:07 pm, 8/7/16 |
| Yadier Molina | Purple Cobras | DROP | to FA | 6:52 pm, 8/7/16 |
| Adonis Garcia | Dead Rabbits | DROP | to FA | 9:23 am, 8/7/16 |
| Albert Almora | Dead Rabbits | DROP | to FA | 9:21 am, 8/7/16 |
| Nick Neidert | Supreme Clientele | DROP | to FA | 7:22 am, 8/7/16 |
| Jarred Cosart | Supreme Clientele | DROP | to FA | 7:10 am, 8/7/16 |
| Austin Gomber | The Bluth Company | DROP | to FA | 10:38 pm, 8/6/16 |
| Steve Pearce | Supreme Clientele | DROP | to FA | 4:53 pm, 8/6/16 |
| Koji Uehara | Supreme Clientele | DROP | to FA | 4:53 pm, 8/6/16 |
| Eric Jagielo | Bridge Four | DROP | to FA | 5:12 pm, 8/5/16 |
| Nick Neidert | Supreme Clientele | DROP | to FA | 10:44 am, 8/5/16 |
| Ryan Vogelsong | Supreme Clientele | DROP | to FA | 9:34 am, 8/5/16 |
| Nate Smith | Supreme Clientele | DROP | to FA | 9:34 am, 8/5/16 |
| Marwin Gonzalez | Cowboys From Hell | DROP | to FA | 9:36 pm, 8/4/16 |
| Ashe Russell | Dead Rabbits | DROP | to FA | 9:20 pm, 8/4/16 |
| James McCann | Cowboys From Hell | DROP | to FA | 8:38 pm, 8/4/16 |
| Dalton Pompey | Dead Rabbits | DROP | to FA | 5:50 pm, 8/4/16 |
| Justin Morneau | The Bluth Company | DROP | to FA | 4:19 pm, 8/4/16 |