| Player | Team | Action | Details | |
|---|---|---|---|---|
| Joel Peralta | Banana Hammock | DROP | to FA | 11:09 am, 5/22/16 |
| Adam Morgan | The Bluth Company | DROP | to FA | 10:02 am, 5/22/16 |
| Joan Gregorio | The Bluth Company | DROP | to FA | 7:36 pm, 5/21/16 |
| Chris Devenski | Supreme Clientele | DROP | to FA | 7:11 pm, 5/21/16 |
| Mike Wright | Supreme Clientele | DROP | to FA | 7:11 pm, 5/21/16 |
| Keon Broxton | Supreme Clientele | DROP | to FA | 7:11 pm, 5/21/16 |
| John Gant | Purple Cobras | DROP | to FA | 10:16 am, 5/21/16 |
| Chase Headley | Geckos | DROP | to FA | 1:06 am, 5/21/16 |
| Chris Coghlan | Geckos | DROP | to FA | 1:05 am, 5/21/16 |
| Kendry Flores | Geckos | DROP | to FA | 1:03 am, 5/21/16 |
| Justin Smoak | Supreme Clientele | DROP | to FA | 6:52 pm, 5/20/16 |
| Anthony Banda | The Bluth Company | DROP | to FA | 5:44 pm, 5/20/16 |
| Ross Stripling | Chinballs | DROP | to FA | 12:55 pm, 5/20/16 |
| Tyler Wilson | Chinballs | DROP | to FA | 12:55 pm, 5/20/16 |
| Nolan Reimold | Shaolin Schmeckles | DROP | to FA | 12:23 pm, 5/20/16 |
| Miguel Castro | Supreme Clientele | DROP | to FA | 12:07 pm, 5/20/16 |
| Tony Cingrani | Supreme Clientele | DROP | to FA | 12:07 pm, 5/20/16 |
| Dariel Alvarez | Dead Rabbits | DROP | to FA | 9:10 pm, 5/19/16 |
| Sean O'Sullivan | Dead Rabbits | DROP | to FA | 12:53 pm, 5/19/16 |
| Ruddy Giron | Nixon's Nasty Ninjas | DROP | to FA | 10:43 am, 5/19/16 |
| Daniel Hudson | Cowboys From Hell | DROP | to FA | 9:56 am, 5/19/16 |
| Monte Harrison | Cowboys From Hell | DROP | to FA | 9:50 am, 5/19/16 |
| R.A. Dickey | The Bluth Company | DROP | to FA | 8:37 am, 5/19/16 |
| Logan Verrett | Geckos | DROP | to FA | 12:34 am, 5/19/16 |
| Ubaldo Jimenez | Geckos | DROP | to FA | 12:34 am, 5/19/16 |