| Player | Team | Action | Details | |
|---|---|---|---|---|
| Billy McKinney | Supreme Clientele | DROP | to FA | 4:45 pm, 4/29/16 |
| Jedd Gyorko | Jon Voight's Car | DROP | to FA | 2:03 pm, 4/29/16 |
| Zack Godley | Banana Hammock | DROP | to FA | 1:06 pm, 4/29/16 |
| Adam Morgan | The Bluth Company | DROP | to FA | 1:05 pm, 4/29/16 |
| Taylor Jungmann | Banana Hammock | DROP | to FA | 12:56 pm, 4/29/16 |
| Doug Fister | Geckos | DROP | to FA | 2:21 am, 4/29/16 |
| Tony Sipp | Geckos | DROP | to FA | 2:20 am, 4/29/16 |
| Hyun-Soo Kim | Geckos | DROP | to FA | 2:19 am, 4/29/16 |
| Joe Blanton | Cowboys From Hell | DROP | to FA | 3:26 pm, 4/28/16 |
| D.J. Peterson | Young Tommy Toolsheds | DROP | to FA | 12:35 pm, 4/28/16 |
| Nick Vincent | Chinballs | DROP | to FA | 12:21 pm, 4/28/16 |
| Jayson Werth | Purple Cobras | DROP | to FA | 11:59 am, 4/28/16 |
| Pedro Strop | Chinballs | DROP | to FA | 10:59 am, 4/28/16 |
| R.A. Dickey | Geckos | DROP | to FA | 1:27 am, 4/28/16 |
| Albert Abreu | The Bluth Company | DROP | to FA | 12:11 am, 4/28/16 |
| Cody Anderson | The Red Barons | DROP | to FA | 5:16 pm, 4/27/16 |
| Luis Urias | Banana Hammock | DROP | to FA | 2:01 pm, 4/27/16 |
| Ryan Raburn | The Bluth Company | DROP | to FA | 12:06 pm, 4/27/16 |
| CC Sabathia | Supreme Clientele | DROP | to FA | 11:09 am, 4/27/16 |
| Tony Cingrani | Supreme Clientele | DROP | to FA | 10:47 am, 4/27/16 |
| Jordy Mercer | Kimble's Kids | DROP | to FA | 6:59 am, 4/27/16 |
| Sean Rodriguez | Geckos | DROP | to FA | 3:05 am, 4/27/16 |
| Dom Nunez | Purple Cobras | DROP | to FA | 9:50 pm, 4/26/16 |
| Coco Crisp | Purple Cobras | DROP | to FA | 9:35 pm, 4/26/16 |
| Nick Hundley | Supreme Clientele | DROP | to FA | 8:25 pm, 4/26/16 |