| Player | Team | Action | Details | |
|---|---|---|---|---|
| Nick Burdi | Young Tommy Toolsheds | DROP | to FA | 10:08 am, 5/9/16 |
| Michael Brantley | Young Tommy Toolsheds | DROP | to FA | 8:57 am, 5/9/16 |
| Harold Ramirez | Scranton Yankees | DROP | to FA | 8:10 am, 5/9/16 |
| Tommy Milone | Dead Rabbits | DROP | to FA | 11:36 pm, 5/8/16 |
| Ender Inciarte | Dead Rabbits | DROP | to FA | 11:36 pm, 5/8/16 |
| Brian Johnson | Supreme Clientele | DROP | to FA | 10:11 pm, 5/8/16 |
| Matt Adams | Scranton Yankees | DROP | to FA | 8:19 pm, 5/8/16 |
| Mike Napoli | Nixon's Nasty Ninjas | DROP | to FA | 7:30 pm, 5/8/16 |
| Miguel Andujar | The Bluth Company | DROP | to FA | 5:29 pm, 5/8/16 |
| Steve Pearce | Purple Cobras | DROP | to FA | 4:57 pm, 5/8/16 |
| Danny Santana | Purple Cobras | DROP | to FA | 4:48 pm, 5/8/16 |
| Melvin Upton Jr. | Scranton Yankees | DROP | to FA | 10:36 pm, 5/7/16 |
| Pablo Sandoval | Scranton Yankees | DROP | to FA | 10:10 pm, 5/7/16 |
| Ryan Howard | Dead Rabbits | DROP | to FA | 5:11 pm, 5/7/16 |
| Caleb Cotham | Bridge Four | DROP | to FA | 4:22 pm, 5/7/16 |
| Logan Verrett | Dead Rabbits | DROP | to FA | 1:35 pm, 5/7/16 |
| Sean Doolittle | Dead Rabbits | DROP | to FA | 1:34 pm, 5/7/16 |
| Tyler Naquin | The Red Barons | DROP | to FA | 1:05 pm, 5/7/16 |
| John Gant | Purple Cobras | DROP | to FA | 1:32 am, 5/7/16 |
| John Axford | Kimble's Kids | DROP | to FA | 10:30 pm, 5/6/16 |
| Trayce Thompson | Supreme Clientele | DROP | to FA | 9:54 pm, 5/6/16 |
| Jered Weaver | Geckos | DROP | to FA | 8:15 pm, 5/6/16 |
| Jorge Lopez | Banana Hammock | DROP | to FA | 2:24 pm, 5/6/16 |
| Chris Shaw | Jon Voight's Car | DROP | to FA | 2:07 pm, 5/6/16 |
| Edmundo Sosa | Jon Voight's Car | DROP | to FA | 1:20 pm, 5/6/16 |