| Player | Team | Action | Details | |
|---|---|---|---|---|
| Enrique Hernandez | The Red Barons | ADD | to MLB | 11:34 am, 5/18/22 |
| Christopher Morel | Ye Olde Tom Toolshed | ADD | to MLB | 6:49 am, 5/18/22 |
| Brandon Crawford | Shaolin Schmeckles | ADD | to MLB | 11:03 pm, 5/17/22 |
| Adam Duvall | Shaolin Schmeckles | ADD | to MLB | 11:03 pm, 5/17/22 |
| Emilio Pagán | Supreme Clientele | ADD | to MLB | 3:05 pm, 5/17/22 |
| Joey Wendle | Supreme Clientele | ADD | to MLB | 3:04 pm, 5/17/22 |
| Cody Poteet | Chinballs | ADD | to MLB | 7:04 am, 5/17/22 |
| Bryce Miller | The Bluth Company | ADD | to AAA | 5:11 pm, 5/16/22 |
| Brock Burke | Cowboys From Hell | ADD | to MLB | 2:49 pm, 5/16/22 |
| Yonathan Daza | Geckos | ADD | to MLB | 11:35 am, 5/16/22 |
| Trevor Williams | Undead Rabbits | ADD | to MLB | 11:30 am, 5/16/22 |
| Brendan Donovan | The Bluth Company | ADD | to AAA | 11:24 am, 5/16/22 |
| Reese Olson | The Bluth Company | ADD | to AA | 9:43 am, 5/16/22 |
| Wade Miley | Bullet Club | ADD | to MLB | 8:22 am, 5/16/22 |
| Jurickson Profar | Shaolin Schmeckles | ADD | to MLB | 8:09 am, 5/16/22 |
| Griff McGarry | The Bluth Company | ADD | to AA | 12:28 am, 5/16/22 |
| Warming Bernabel | Monk's Café | ADD | to A | 10:09 pm, 5/15/22 |
| Bryce Ball | The Bluth Company | ADD | to AAA | 9:52 pm, 5/15/22 |
| Eddys Leonard | Chinballs | ADD | to AAA | 8:21 pm, 5/15/22 |
| Michael Grove | The Bluth Company | ADD | to AAA | 7:45 pm, 5/14/22 |
| Alec Marsh | The Red Barons | ADD | to A | 11:18 am, 5/14/22 |
| Devin Smeltzer | Bullet Club | ADD | to MLB | 11:00 am, 5/14/22 |
| Beau Brieske | Bullet Club | ADD | to MLB | 10:24 am, 5/14/22 |
| Griffin Jax | Cowboys From Hell | ADD | to MLB | 6:44 pm, 5/13/22 |
| Noah Song | Undead Rabbits | ADD | to AAA | 1:38 pm, 5/13/22 |