| Player | Team | Action | Details | |
|---|---|---|---|---|
| Jorge Alfaro | Monk's Café | ADD | to MLB | 11:00 am, 4/28/22 |
| Calvin Mitchell | Bullet Club | ADD | to MLB | 10:38 am, 4/28/22 |
| Jake Burger | Geckos | ADD | to AAA | 3:06 pm, 4/27/22 |
| Alex Binelas | Chinballs | ADD | to A | 2:38 pm, 4/27/22 |
| Moises Gomez | Shaolin Schmeckles | ADD | to AAA | 9:51 am, 4/27/22 |
| Wilmer Flores | Bullet Club | ADD | to MLB | 8:52 am, 4/27/22 |
| Marco Raya | The Bluth Company | ADD | to A | 8:09 am, 4/27/22 |
| Craig Stammen | Nixon's Nasty Ninjas | ADD | to MLB | 9:36 pm, 4/26/22 |
| Drew Smith | Geckos | ADD | to MLB | 5:28 pm, 4/26/22 |
| Miguel Andujar | Cowboys From Hell | ADD | to MLB | 5:26 pm, 4/26/22 |
| Andrew Abbott | Geckos | ADD | to AA | 2:10 pm, 4/26/22 |
| Devin Williams | The Bluth Company | ADD | to MLB | 1:02 pm, 4/26/22 |
| Dany Jimenez | Shaolin Schmeckles | ADD | to MLB | 11:32 am, 4/26/22 |
| Michael Chavis | Bullet Club | ADD | to MLB | 11:26 am, 4/26/22 |
| Chris Stratton | Shaolin Schmeckles | ADD | to MLB | 11:09 am, 4/26/22 |
| Michael King | The Bluth Company | ADD | to MLB | 11:01 am, 4/26/22 |
| Hector Neris | Kimble's Kids | ADD | to MLB | 10:49 am, 4/26/22 |
| Christian Encarnacion-Strand | Chinballs | ADD | to A | 10:20 am, 4/26/22 |
| Alex Binelas | Chinballs | ADD | to A | 3:56 am, 4/26/22 |
| Dominic Smith | Geckos | ADD | to MLB | 1:05 pm, 4/25/22 |
| Cesar Prieto | The Bluth Company | ADD | to AAA | 1:04 pm, 4/25/22 |
| Griff McGarry | The Bluth Company | ADD | to AA | 1:01 pm, 4/25/22 |
| Brandon Walter | The Bluth Company | ADD | to AA | 12:59 pm, 4/25/22 |
| Jake Junis | Ye Olde Tom Toolshed | ADD | to MLB | 11:24 am, 4/25/22 |
| Ji-Man Choi | Supreme Clientele | ADD | to MLB | 11:02 am, 4/25/22 |