| Player | Team | Action | Details | |
|---|---|---|---|---|
| Luis Guillorme | Cowboys From Hell | ADD | to MLB | 6:50 am, 5/31/22 |
| Nick Plummer | Bullet Club | ADD | to MLB | 9:22 pm, 5/30/22 |
| Kyle Farmer | Scranton Yankees | ADD | to MLB | 9:19 pm, 5/30/22 |
| J.P. Crawford | Scranton Yankees | ADD | to MLB | 9:19 pm, 5/30/22 |
| Chris Archer | Scranton Yankees | ADD | to MLB | 9:17 pm, 5/30/22 |
| Angel Zerpa | Scranton Yankees | ADD | to AAA | 9:14 pm, 5/30/22 |
| Ji-Hwan Bae | The Bluth Company | ADD | to AAA | 11:56 am, 5/30/22 |
| Jorge Mateo | Bullet Club | ADD | to MLB | 6:54 am, 5/30/22 |
| Mitchell White | Chinballs | ADD | to MLB | 3:26 am, 5/30/22 |
| Kole Calhoun | Chinballs | ADD | to MLB | 2:47 am, 5/30/22 |
| Edwin Rios | Chinballs | ADD | to MLB | 2:47 am, 5/30/22 |
| Casey Schmitt | The Red Barons | ADD | to AA | 12:54 am, 5/30/22 |
| Sam Hentges | The Red Barons | ADD | to AAA | 11:52 pm, 5/29/22 |
| Erick Fedde | Bullet Club | ADD | to MLB | 10:35 pm, 5/29/22 |
| Eduardo Escobar | Cowboys From Hell | ADD | to MLB | 7:56 pm, 5/29/22 |
| Evan Longoria | The Red Barons | ADD | to MLB | 4:16 am, 5/29/22 |
| Aaron Sabato | The Red Barons | ADD | to A | 4:10 am, 5/29/22 |
| Colin Poche | The Red Barons | ADD | to MLB | 4:08 am, 5/29/22 |
| Franchy Cordero | Monk's Café | ADD | to MLB | 11:24 am, 5/28/22 |
| Oscar Gonzalez | Monk's Café | ADD | to MLB | 11:18 am, 5/28/22 |
| Gabriel Arias | The Red Barons | ADD | to A | 11:53 am, 5/27/22 |
| Brian Anderson | The Red Barons | ADD | to MLB | 11:20 am, 5/27/22 |
| Nick Anderson | The Red Barons | ADD | to MLB | 11:20 am, 5/27/22 |
| Bailey Falter | Bullet Club | ADD | to MLB | 8:57 am, 5/27/22 |
| Devin Smeltzer | Undead Rabbits | ADD | to AAA | 12:51 am, 5/27/22 |