| Player | Team | Action | Details | |
|---|---|---|---|---|
| Dillon Peters | Shaolin Schmeckles | ADD | to MLB | 3:03 am, 8/26/21 |
| Jordan Romano | Ye Olde Tom Toolshed | ADD | to MLB | 7:48 pm, 8/25/21 |
| Eddys Leonard | The Bluth Company | ADD | to A | 7:29 pm, 8/25/21 |
| Brent Suter | The Red Barons | ADD | to MLB | 4:18 pm, 8/25/21 |
| Yadiel Hernandez | Chinballs | ADD | to MLB | 1:09 pm, 8/25/21 |
| Lane Thomas | The Red Barons | ADD | to MLB | 12:37 pm, 8/25/21 |
| Brian Anderson | Geckos | ADD | to MLB | 11:35 am, 8/25/21 |
| Seth Lugo | The Red Barons | ADD | to MLB | 10:06 am, 8/24/21 |
| Emmanuel Rivera | Cowboys From Hell | ADD | to MLB | 9:11 am, 8/24/21 |
| Garrett Hampson | The Red Barons | ADD | to MLB | 9:00 am, 8/24/21 |
| Andy Ibanez | The Red Barons | ADD | to MLB | 9:00 am, 8/24/21 |
| Corey Knebel | Shaolin Schmeckles | ADD | to MLB | 3:13 am, 8/24/21 |
| Clayton Beeter | The Bluth Company | ADD | to AA | 11:36 pm, 8/23/21 |
| Jake McCarthy | Ye Olde Tom Toolshed | ADD | to AAA | 4:41 pm, 8/23/21 |
| Adam Ottavino | Shaolin Schmeckles | ADD | to MLB | 4:39 pm, 8/23/21 |
| Humberto Mejia | Shaolin Schmeckles | ADD | to MLB | 12:21 pm, 8/23/21 |
| Paul Blackburn | Shaolin Schmeckles | ADD | to MLB | 12:21 pm, 8/23/21 |
| Victor Gonzalez | Shaolin Schmeckles | ADD | to MLB | 3:29 pm, 8/22/21 |
| Phil Bickford | Shaolin Schmeckles | ADD | to MLB | 3:15 pm, 8/22/21 |
| Jake Diekman | Kimble's Kids | ADD | to MLB | 12:59 pm, 8/22/21 |
| Justin Upton | Kimble's Kids | ADD | to MLB | 12:58 pm, 8/22/21 |
| Miguel Cabrera | Kimble's Kids | ADD | to MLB | 12:58 pm, 8/22/21 |
| Odubel Herrera | Cowboys From Hell | ADD | to MLB | 10:34 am, 8/22/21 |
| Drey Jameson | Cowboys From Hell | ADD | to AA | 8:13 am, 8/21/21 |
| Dillon Peters | Shaolin Schmeckles | ADD | to MLB | 3:12 am, 8/21/21 |