| Player | Team | Action | Details | |
|---|---|---|---|---|
| Dustin Harris | The Bluth Company | ADD | to AA | 11:32 am, 8/31/21 |
| Jorge Alfaro | The Red Barons | ADD | to MLB | 6:51 am, 8/31/21 |
| Gio Urshela | The Red Barons | ADD | to MLB | 6:51 am, 8/31/21 |
| D.J. Peters | Bullet Club | ADD | to MLB | 7:52 pm, 8/30/21 |
| Jorbit Vivas | Purple Cobras | ADD | to A | 10:28 am, 8/30/21 |
| Edmundo Sosa | Bullet Club | ADD | to MLB | 10:20 am, 8/30/21 |
| Austin Hays | Purple Cobras | ADD | to MLB | 9:07 am, 8/30/21 |
| Jorge Mateo | The Red Barons | ADD | to MLB | 10:11 pm, 8/29/21 |
| Yasel Antuna | The Red Barons | ADD | to MLB | 10:10 pm, 8/29/21 |
| Bradley Zimmer | Purple Cobras | ADD | to MLB | 9:15 am, 8/29/21 |
| Eli Morgan | Purple Cobras | ADD | to AAA | 12:59 am, 8/29/21 |
| Taylor Hearn | Bullet Club | ADD | to MLB | 12:07 am, 8/29/21 |
| Taylor Motter | Shaolin Schmeckles | ADD | to MLB | 8:29 pm, 8/28/21 |
| Clayton Beeter | Cowboys From Hell | ADD | to AA | 5:13 pm, 8/28/21 |
| Carlos Estevez | Shaolin Schmeckles | ADD | to MLB | 2:23 am, 8/28/21 |
| Tyler Wade | Undead Rabbits | ADD | to MLB | 7:31 pm, 8/27/21 |
| Erick Fedde | Undead Rabbits | ADD | to MLB | 7:30 pm, 8/27/21 |
| Wandy Peralta | The Red Barons | ADD | to MLB | 12:22 pm, 8/27/21 |
| Jose Suarez | The Red Barons | ADD | to MLB | 12:22 pm, 8/27/21 |
| Paul Blackburn | The Red Barons | ADD | to MLB | 12:20 pm, 8/27/21 |
| Logan S. Allen | Cowboys From Hell | ADD | to MLB | 5:54 am, 8/27/21 |
| Dallas Keuchel | The Red Barons | ADD | to MLB | 11:21 am, 8/26/21 |
| Adam Engel | Ye Olde Tom Toolshed | ADD | to MLB | 9:48 am, 8/26/21 |
| Kevin Smith | Purple Cobras | ADD | to NA | 7:49 am, 8/26/21 |
| Jamie Barria | Cowboys From Hell | ADD | to MLB | 4:09 am, 8/26/21 |