| Player | Team | Action | Details | |
|---|---|---|---|---|
| Bryce Elder | Purple Cobras | ADD | to A | 8:26 pm, 9/10/21 |
| Matt Brash | Purple Cobras | ADD | to AA | 8:26 pm, 9/10/21 |
| Andrew Heaney | Bullet Club | ADD | to MLB | 12:01 am, 9/10/21 |
| Harrison Bader | Chinballs | ADD | to MLB | 1:20 pm, 9/9/21 |
| Yadier Molina | Purple Cobras | ADD | to MLB | 9:35 am, 9/9/21 |
| Jose Suarez | The Bluth Company | ADD | to AAA | 11:40 pm, 9/8/21 |
| Mitchell White | The Bluth Company | ADD | to AAA | 9:43 am, 9/7/21 |
| Ryne Nelson | Supreme Clientele | ADD | to AAA | 10:43 am, 9/6/21 |
| Drew Smyly | Supreme Clientele | ADD | to MLB | 10:41 am, 9/6/21 |
| Zac Lowther | The Red Barons | ADD | to MLB | 9:58 am, 9/6/21 |
| Thairo Estrada | The Bluth Company | ADD | to AAA | 8:12 pm, 9/5/21 |
| Austin Hays | Purple Cobras | ADD | to MLB | 7:34 pm, 9/5/21 |
| Janson Junk | The Bluth Company | ADD | to AAA | 10:22 am, 9/5/21 |
| Lorenzo Cain | Purple Cobras | ADD | to MLB | 5:36 am, 9/5/21 |
| Lane Thomas | Bullet Club | ADD | to MLB | 7:18 pm, 9/4/21 |
| Rowan Wick | Purple Cobras | ADD | to MLB | 8:57 am, 9/4/21 |
| Taylor Motter | Shaolin Schmeckles | ADD | to MLB | 5:19 pm, 9/3/21 |
| Dallas Keuchel | Bullet Club | ADD | to MLB | 7:01 am, 9/3/21 |
| Jose Siri | Bullet Club | ADD | to AAA | 5:59 am, 9/3/21 |
| Joey Wendle | Purple Cobras | ADD | to MLB | 3:52 am, 9/3/21 |
| Jose Suarez | The Bluth Company | ADD | to AAA | 6:47 pm, 9/2/21 |
| Hector Neris | Undead Rabbits | ADD | to MLB | 5:51 pm, 9/2/21 |
| Jorge Alfaro | Bullet Club | ADD | to MLB | 4:24 pm, 9/2/21 |
| Trevor Stephan | Ye Olde Tom Toolshed | ADD | to MLB | 2:25 pm, 9/2/21 |
| Paolo Espino | Ye Olde Tom Toolshed | ADD | to MLB | 2:25 pm, 9/2/21 |