| Player | Team | Action | Details | |
|---|---|---|---|---|
| Sheldon Neuse | Ye Olde Tom Toolshed | ADD | to AAA | 3:46 pm, 8/11/21 |
| Matthew Frazier | The Bluth Company | ADD | to AA | 1:22 pm, 8/11/21 |
| Bradley Zimmer | The Red Barons | ADD | to MLB | 11:42 am, 8/11/21 |
| Josh Harrison | Purple Cobras | ADD | to MLB | 10:28 am, 8/11/21 |
| Corey Knebel | Shaolin Schmeckles | ADD | to MLB | 3:56 am, 8/11/21 |
| Zack Littell | Shaolin Schmeckles | ADD | to AAA | 1:04 am, 8/11/21 |
| Michael A. Taylor | Scranton Yankees | ADD | to MLB | 11:07 pm, 8/10/21 |
| Steven Brault | Bullet Club | ADD | to MLB | 10:35 pm, 8/10/21 |
| Donovan Solano | Scranton Yankees | ADD | to MLB | 8:52 pm, 8/10/21 |
| Rowdy Tellez | Scranton Yankees | ADD | to MLB | 8:52 pm, 8/10/21 |
| Jordan Lyles | Scranton Yankees | ADD | to MLB | 8:50 pm, 8/10/21 |
| Jake Arrieta | Scranton Yankees | ADD | to MLB | 8:49 pm, 8/10/21 |
| Will Crowe | Scranton Yankees | ADD | to MLB | 8:49 pm, 8/10/21 |
| Ken Waldichuk | The Bluth Company | ADD | to AA | 7:22 pm, 8/10/21 |
| Ramon Urias | The Red Barons | ADD | to MLB | 7:00 pm, 8/10/21 |
| Trevor May | Geckos | ADD | to MLB | 1:41 pm, 8/10/21 |
| Brian Goodwin | Geckos | ADD | to MLB | 1:41 pm, 8/10/21 |
| Miguel Rojas | Geckos | ADD | to MLB | 1:41 pm, 8/10/21 |
| Brandon Pfaadt | Purple Cobras | ADD | to A | 7:45 am, 8/10/21 |
| Austin Allen | Purple Cobras | ADD | to AAA | 7:33 am, 8/10/21 |
| Blaze Jordan | Purple Cobras | ADD | to A | 7:04 am, 8/10/21 |
| Aledmys Diaz | Purple Cobras | ADD | to MLB | 6:27 am, 8/10/21 |
| Connor Joe | Purple Cobras | ADD | to AAA | 5:02 am, 8/9/21 |
| Chad Kuhl | The Red Barons | ADD | to MLB | 8:25 am, 8/8/21 |
| Zack Britton | The Red Barons | ADD | to MLB | 8:25 am, 8/8/21 |