| Player | Team | Action | Details | |
|---|---|---|---|---|
| Cole Ragans | The Bluth Company | ADD | to AA | 3:07 pm, 7/12/21 |
| Hoy Jun Park | Ye Olde Tom Toolshed | ADD | to AAA | 11:48 am, 7/12/21 |
| Masyn Winn | The Bluth Company | ADD | to AA | 8:58 pm, 7/11/21 |
| Darin Ruf | Undead Rabbits | ADD | to MLB | 12:49 pm, 7/11/21 |
| Chase De Jong | Undead Rabbits | ADD | to MLB | 9:04 am, 7/11/21 |
| Alvarado Jose | Shaolin Schmeckles | ADD | to MLB | 2:33 pm, 7/10/21 |
| Joe Kelly | Shaolin Schmeckles | ADD | to MLB | 2:24 am, 7/10/21 |
| Rodolfo Castro | The Bluth Company | ADD | to AA | 12:07 am, 7/10/21 |
| Wade LeBlanc | Undead Rabbits | ADD | to MLB | 10:30 am, 7/9/21 |
| Max Kranick | The Bluth Company | ADD | to AA | 1:58 am, 7/9/21 |
| Cristian Santana | Undead Rabbits | ADD | to A | 12:34 am, 7/9/21 |
| Brad Miller | Shaolin Schmeckles | ADD | to MLB | 7:48 pm, 7/8/21 |
| Jeimer Candelario | The Bluth Company | ADD | to MLB | 1:20 pm, 7/8/21 |
| Steven Duggar | The Bluth Company | ADD | to MLB | 1:20 pm, 7/8/21 |
| Archie Bradley | Scranton Yankees | ADD | to MLB | 12:50 pm, 7/8/21 |
| Mike Foltynewicz | Scranton Yankees | ADD | to MLB | 12:39 pm, 7/8/21 |
| Kyle Freeland | Scranton Yankees | ADD | to MLB | 12:39 pm, 7/8/21 |
| Martin Perez | Scranton Yankees | ADD | to MLB | 12:38 pm, 7/8/21 |
| Josh Harrison | Scranton Yankees | ADD | to MLB | 12:37 pm, 7/8/21 |
| Enrique Hernandez | Scranton Yankees | ADD | to MLB | 12:37 pm, 7/8/21 |
| Michael Wacha | Scranton Yankees | ADD | to MLB | 12:35 pm, 7/8/21 |
| Adam Ottavino | Scranton Yankees | ADD | to MLB | 12:34 pm, 7/8/21 |
| Chad Green | Scranton Yankees | ADD | to MLB | 12:34 pm, 7/8/21 |
| Orlando Arcia | Scranton Yankees | ADD | to MLB | 12:34 pm, 7/8/21 |
| J.A. Happ | Bullet Club | ADD | to MLB | 11:10 am, 7/8/21 |