| Player | Team | Action | Details | |
|---|---|---|---|---|
| Andy Ibanez | Shaolin Schmeckles | ADD | to AAA | 8:22 am, 6/22/21 |
| Wilmer Flores | Purple Cobras | ADD | to MLB | 8:17 am, 6/22/21 |
| David Fletcher | The Red Barons | ADD | to MLB | 6:00 am, 6/22/21 |
| Sam Hentges | Supreme Clientele | ADD | to MLB | 12:29 pm, 6/21/21 |
| Harold Ramirez | Supreme Clientele | ADD | to MLB | 12:29 pm, 6/21/21 |
| Joe Gray Jr. | Scranton Yankees | ADD | to MLB | 10:32 am, 6/21/21 |
| Jose Miranda | The Bluth Company | ADD | to AA | 10:29 am, 6/21/21 |
| Zach Logue | Nixon's Nasty Ninjas | ADD | to AAA | 10:26 am, 6/21/21 |
| Anthony Bender | Nixon's Nasty Ninjas | ADD | to MLB | 10:25 am, 6/21/21 |
| Chad Green | The Bluth Company | ADD | to MLB | 10:15 am, 6/21/21 |
| Lamonte Wade | The Bluth Company | ADD | to MLB | 9:56 am, 6/21/21 |
| Collin McHugh | The Bluth Company | ADD | to MLB | 9:56 am, 6/21/21 |
| Zach McKinstry | Purple Cobras | ADD | to AAA | 7:00 am, 6/21/21 |
| Daz Cameron | Bullet Club | ADD | to MLB | 8:12 pm, 6/20/21 |
| Brayan Bello | The Bluth Company | ADD | to A | 3:11 am, 6/20/21 |
| Randy Dobnak | Bullet Club | ADD | to MLB | 10:40 am, 6/19/21 |
| Alec Mills | Supreme Clientele | ADD | to MLB | 4:15 pm, 6/18/21 |
| Michael Wacha | Supreme Clientele | ADD | to MLB | 4:15 pm, 6/18/21 |
| J.C. Mejia | Supreme Clientele | ADD | to MLB | 4:15 pm, 6/18/21 |
| Jahmai Jones | Supreme Clientele | ADD | to MLB | 4:15 pm, 6/18/21 |
| Bruce Zimmermann | Supreme Clientele | ADD | to MLB | 4:14 pm, 6/18/21 |
| Tony Kemp | Supreme Clientele | ADD | to MLB | 4:14 pm, 6/18/21 |
| Austin Hays | Undead Rabbits | ADD | to MLB | 4:08 pm, 6/18/21 |
| Masyn Winn | The Bluth Company | ADD | to AAA | 2:55 pm, 6/18/21 |
| Zach Thompson | The Bluth Company | ADD | to AAA | 10:17 am, 6/18/21 |