| Player | Team | Action | Details | |
|---|---|---|---|---|
| Kyle Higashioka | The Bluth Company | ADD | to MLB | 2:02 pm, 5/4/21 |
| Alec Marsh | The Bluth Company | ADD | to AAA | 2:01 pm, 5/4/21 |
| Keegan Akin | The Bluth Company | ADD | to AAA | 1:33 pm, 5/4/21 |
| Brandon Bielak | Purple Cobras | ADD | to AAA | 7:29 am, 5/4/21 |
| Clayton Beeter | The Bluth Company | ADD | to AAA | 1:48 am, 5/4/21 |
| Jonathan Villar | Supreme Clientele | ADD | to MLB | 6:26 pm, 5/3/21 |
| Dan Vogelbach | Supreme Clientele | ADD | to MLB | 6:26 pm, 5/3/21 |
| Trevor May | Purple Cobras | ADD | to MLB | 4:21 pm, 5/3/21 |
| Michael Tauchman | The Bluth Company | ADD | to MLB | 12:06 pm, 5/3/21 |
| Mauricio Dubon | The Red Barons | ADD | to MLB | 11:08 am, 5/3/21 |
| Isan Diaz | Purple Cobras | ADD | to AAA | 8:30 am, 5/3/21 |
| Rafael Montero | Purple Cobras | ADD | to MLB | 8:36 pm, 5/2/21 |
| Joey Cantillo | The Bluth Company | ADD | to AAA | 8:17 pm, 5/2/21 |
| Asdrubal Cabrera | Purple Cobras | ADD | to MLB | 9:33 am, 5/2/21 |
| Duane Underwood | Undead Rabbits | ADD | to AAA | 1:22 am, 5/2/21 |
| Dom Nunez | Purple Cobras | ADD | to MLB | 1:01 am, 5/2/21 |
| William Contreras | Supreme Clientele | ADD | to AAA | 11:49 pm, 5/1/21 |
| Drew Strotman | The Bluth Company | ADD | to AAA | 10:53 am, 5/1/21 |
| Willi Castro | The Bluth Company | ADD | to AAA | 9:38 am, 5/1/21 |
| Mitch Moreland | Purple Cobras | ADD | to MLB | 7:14 am, 5/1/21 |
| Chris Owings | Purple Cobras | ADD | to MLB | 7:00 am, 5/1/21 |
| Andrew Knizer | Purple Cobras | ADD | to MLB | 6:59 am, 5/1/21 |
| Edwin Uceta | Geckos | ADD | to AAA | 3:19 pm, 4/30/21 |
| Joey Lucchesi | The Bluth Company | ADD | to AAA | 1:30 pm, 4/30/21 |
| Avisail Garcia | Geckos | ADD | to MLB | 12:51 pm, 4/30/21 |