| Player | Team | Action | Details | |
|---|---|---|---|---|
| Garrett Whitlock | Chinballs | ADD | to MLB | 8:14 pm, 4/8/21 |
| Myles Straw | Shaolin Schmeckles | ADD | to MLB | 4:16 pm, 4/8/21 |
| Jake Diekman | Shaolin Schmeckles | ADD | to MLB | 3:35 pm, 4/8/21 |
| Josh Fuentes | Geckos | ADD | to MLB | 1:07 pm, 4/8/21 |
| Jackie Bradley Jr | Geckos | ADD | to MLB | 1:07 pm, 4/8/21 |
| David Bote | Geckos | ADD | to MLB | 1:07 pm, 4/8/21 |
| Huascar Ynoa | Supreme Clientele | ADD | to MLB | 11:27 am, 4/8/21 |
| Gregory Soto | Supreme Clientele | ADD | to MLB | 11:27 am, 4/8/21 |
| Tyler Anderson | Cowboys From Hell | ADD | to MLB | 10:03 am, 4/8/21 |
| Matt Harvey | Cowboys From Hell | ADD | to MLB | 10:03 am, 4/8/21 |
| Jairo Solis | Shaolin Schmeckles | ADD | to AA | 12:33 am, 4/8/21 |
| Ross Stripling | Chinballs | ADD | to MLB | 5:13 pm, 4/7/21 |
| Nick Neidert | Chinballs | ADD | to MLB | 5:13 pm, 4/7/21 |
| Wade Miley | Supreme Clientele | ADD | to MLB | 3:22 pm, 4/7/21 |
| Jake Junis | Bullet Club | ADD | to MLB | 2:08 pm, 4/7/21 |
| Andrew Stevenson | Cowboys From Hell | ADD | to MLB | 11:24 am, 4/7/21 |
| Travis Shaw | Purple Cobras | ADD | to MLB | 10:03 am, 4/7/21 |
| Jonathan Bowlan | Bullet Club | ADD | to AAA | 5:14 pm, 4/6/21 |
| Yasel Antuna | The Red Barons | ADD | to AAA | 10:02 am, 4/6/21 |
| Brandon Bielak | Purple Cobras | ADD | to AAA | 5:05 am, 4/6/21 |
| Evan Longoria | Purple Cobras | ADD | to MLB | 4:57 am, 4/6/21 |
| Drew Strotman | The Bluth Company | ADD | to AA | 12:16 am, 4/6/21 |
| Brandon Williamson | Geckos | ADD | to AA | 10:43 pm, 4/5/21 |
| Omar Narvaez | Purple Cobras | ADD | to MLB | 7:07 pm, 4/5/21 |
| Carter Kieboom | Chinballs | ADD | to AA | 1:41 pm, 4/5/21 |