| Player | Team | Action | Details | |
|---|---|---|---|---|
| Matt Moore | Supreme Clientele | ADD | to MLB | 12:00 am, 3/16/21 |
| Chris Flexen | Supreme Clientele | ADD | to MLB | 12:00 am, 3/16/21 |
| Jackie Bradley Jr | Kimble's Kids | ADD | to MLB | 12:00 am, 3/16/21 |
| Odubel Herrera | Bullet Club | ADD | to MLB | 11:57 pm, 3/15/21 |
| Gilberto Celestino | Shaolin Schmeckles | ADD | to AA | 11:54 pm, 3/15/21 |
| Myles Straw | Purple Cobras | ADD | to MLB | 11:53 pm, 3/15/21 |
| Bobby Bradley | Supreme Clientele | ADD | to MLB | 11:51 pm, 3/15/21 |
| Hunter Brown | The Red Barons | ADD | to AAA | 11:51 pm, 3/15/21 |
| Jurickson Profar | Supreme Clientele | ADD | to MLB | 11:50 pm, 3/15/21 |
| Enrique Hernandez | Undead Rabbits | ADD | to MLB | 11:50 pm, 3/15/21 |
| Michael Wacha | Supreme Clientele | ADD | to MLB | 11:50 pm, 3/15/21 |
| Carlos Santana | Undead Rabbits | ADD | to MLB | 11:50 pm, 3/15/21 |
| Buster Posey | Supreme Clientele | ADD | to MLB | 11:50 pm, 3/15/21 |
| Craig Kimbrel | Undead Rabbits | ADD | to MLB | 11:49 pm, 3/15/21 |
| Aaron Sanchez | Bullet Club | ADD | to MLB | 11:45 pm, 3/15/21 |
| Steven Matz | Cowboys From Hell | ADD | to MLB | 11:36 pm, 3/15/21 |
| Jake McGee | Geckos | ADD | to MLB | 11:30 pm, 3/15/21 |
| Gilberto Jimenez | Purple Cobras | ADD | to A | 11:27 pm, 3/15/21 |
| Yimi Garcia | Purple Cobras | ADD | to MLB | 10:59 pm, 3/15/21 |
| Alex Cobb | The Red Barons | ADD | to MLB | 10:49 pm, 3/15/21 |
| Daniel Poncedeleon | The Red Barons | ADD | to MLB | 10:49 pm, 3/15/21 |
| Seth Romero | Geckos | ADD | to AA | 10:40 pm, 3/15/21 |
| Aaron Ashby | Purple Cobras | ADD | to AAA | 10:34 pm, 3/15/21 |
| Jackson Holliday | Bridge Four | ADD | to Draft Pick | 10:30 am, 1/27/21 |
| Austin Slater | Purple Cobras | ADD | to MLB | 10:12 am, 1/18/21 |