| Player | Team | Action | Details | |
|---|---|---|---|---|
| Luis Garcia | The Red Barons | DROP | to FA | 6:53 am, 9/1/22 |
| Robert Suarez | The Red Barons | DROP | to FA | 6:08 am, 9/1/22 |
| Luis Garcia | The Bluth Company | DROP | to FA | 4:52 pm, 8/31/22 |
| Joey Gallo | The Bluth Company | DROP | to FA | 4:51 pm, 8/31/22 |
| Chris Archer | Geckos | DROP | to FA | 1:24 pm, 8/31/22 |
| Chris Flexen | Supreme Clientele | DROP | to FA | 12:11 pm, 8/31/22 |
| Brad Keller | Supreme Clientele | DROP | to FA | 12:11 pm, 8/31/22 |
| Will Benson | Supreme Clientele | DROP | to FA | 12:10 pm, 8/31/22 |
| Freddy Tarnok | The Bluth Company | DROP | to FA | 1:01 am, 8/31/22 |
| Ryan Rolison | Ye Olde Tom Toolshed | DROP | to FA | 2:20 pm, 8/30/22 |
| Yusei Kikuchi | Ye Olde Tom Toolshed | DROP | to FA | 2:15 pm, 8/30/22 |
| Jake Junis | Ye Olde Tom Toolshed | DROP | to FA | 2:15 pm, 8/30/22 |
| Jake Burger | The Red Barons | DROP | to FA | 6:17 am, 8/30/22 |
| Jonathan Villar | The Red Barons | DROP | to FA | 9:23 pm, 8/29/22 |
| Marcell Ozuna | Shaolin Schmeckles | DROP | to FA | 5:10 pm, 8/29/22 |
| Paul DeJong | Shaolin Schmeckles | DROP | to FA | 5:10 pm, 8/29/22 |
| Jurickson Profar | Shaolin Schmeckles | DROP | to FA | 5:09 pm, 8/29/22 |
| Corey Dickerson | Bullet Club | DROP | to FA | 10:40 am, 8/29/22 |
| Samuel Zavala | Chinballs | DROP | to FA | 2:36 am, 8/29/22 |
| Michael Grove | The Red Barons | DROP | to FA | 12:50 am, 8/28/22 |
| Alex Wood | The Red Barons | DROP | to FA | 12:12 am, 8/28/22 |
| Jose Salas | The Red Barons | DROP | to FA | 11:21 pm, 8/27/22 |
| Gabriel Arias | The Red Barons | DROP | to FA | 10:03 pm, 8/27/22 |
| Jack Suwinski | The Red Barons | DROP | to FA | 9:55 pm, 8/27/22 |
| Tyler Naquin | Bullet Club | DROP | to FA | 6:03 pm, 8/27/22 |