| Player | Team | Action | Details | |
|---|---|---|---|---|
| Joe Boyle | Geckos | DROP | to FA | 7:31 pm, 8/26/22 |
| Jose Butto | Geckos | DROP | to FA | 7:26 pm, 8/26/22 |
| Connor Joe | Bullet Club | DROP | to FA | 5:03 pm, 8/26/22 |
| Ramon Urias | Chinballs | DROP | to FA | 11:16 am, 8/26/22 |
| Brendan Donovan | Chinballs | DROP | to FA | 11:16 am, 8/26/22 |
| Ethan Small | Chinballs | DROP | to FA | 10:02 am, 8/26/22 |
| Bryan Abreu | The Red Barons | DROP | to FA | 7:50 pm, 8/25/22 |
| Jack Suwinski | The Red Barons | DROP | to FA | 7:49 pm, 8/25/22 |
| Mike Yastrzemski | Undead Rabbits | DROP | to FA | 11:57 am, 8/25/22 |
| Francisco Mejia | Undead Rabbits | DROP | to FA | 11:56 am, 8/25/22 |
| Adam Frazier | Undead Rabbits | DROP | to FA | 11:56 am, 8/25/22 |
| Whit Merrifield | Chinballs | DROP | to FA | 7:51 am, 8/25/22 |
| Luis Rengifo | Chinballs | DROP | to FA | 7:51 am, 8/25/22 |
| Mike Moustakas | The Red Barons | DROP | to FA | 7:08 am, 8/25/22 |
| Tucker Davidson | The Red Barons | DROP | to FA | 7:08 am, 8/25/22 |
| Kris Bubic | The Bluth Company | DROP | to FA | 9:58 pm, 8/24/22 |
| Zach Plesac | The Bluth Company | DROP | to FA | 9:58 pm, 8/24/22 |
| David Peralta | Bullet Club | DROP | to FA | 3:27 pm, 8/22/22 |
| Emmanuel Rivera | Bullet Club | DROP | to FA | 3:27 pm, 8/22/22 |
| James Paxton | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |
| Enrique Hernandez | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |
| Riley Adams | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |
| J.D. Davis | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |
| Kolten Wong | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |
| Michael Grove | The Red Barons | DROP | to FA | 1:12 pm, 8/22/22 |