| Player | Team | Action | Details | |
|---|---|---|---|---|
| Vaun Brown | Monk's Café | DROP | to FA | 11:25 pm, 8/8/22 |
| Christian Vazquez | Undead Rabbits | DROP | to FA | 5:54 pm, 8/8/22 |
| Jesus Aguilar | Geckos | DROP | to FA | 4:22 pm, 8/8/22 |
| Joe Mantiply | Chinballs | DROP | to FA | 11:13 am, 8/8/22 |
| Luis Rengifo | The Red Barons | DROP | to FA | 6:36 am, 8/8/22 |
| Tucker Davidson | The Red Barons | DROP | to FA | 6:36 am, 8/8/22 |
| Patrick Corbin | Geckos | DROP | to FA | 1:25 pm, 8/7/22 |
| Domingo German | The Bluth Company | DROP | to FA | 9:33 am, 8/7/22 |
| Chris Archer | Scranton Yankees | DROP | to FA | 9:01 am, 8/7/22 |
| Zack Greinke | Shaolin Schmeckles | DROP | to FA | 12:27 am, 8/7/22 |
| Hunter Gaddis | The Bluth Company | DROP | to FA | 9:43 pm, 8/6/22 |
| Zach Plesac | Monk's Café | DROP | to FA | 9:24 pm, 8/6/22 |
| Jake Burger | Chinballs | DROP | to FA | 9:23 pm, 8/6/22 |
| Jordan Hicks | Monk's Café | DROP | to FA | 9:16 pm, 8/6/22 |
| Tommy Pham | Chinballs | DROP | to FA | 9:16 pm, 8/6/22 |
| Mike Yastrzemski | Monk's Café | DROP | to FA | 9:15 pm, 8/6/22 |
| Leandro Cedeno | Monk's Café | DROP | to FA | 9:10 pm, 8/6/22 |
| Joe Jimenez | Geckos | DROP | to FA | 8:48 pm, 8/6/22 |
| Brailyn Marquez | The Red Barons | DROP | to FA | 10:29 am, 8/6/22 |
| Austin Slater | Chinballs | DROP | to FA | 4:05 am, 8/6/22 |
| Trayce Thompson | Chinballs | DROP | to FA | 4:05 am, 8/6/22 |
| Mark Melancon | Chinballs | DROP | to FA | 4:04 am, 8/6/22 |
| Darin Ruf | Chinballs | DROP | to FA | 4:04 am, 8/6/22 |
| Giovanny Gallegos | Chinballs | DROP | to FA | 4:03 am, 8/6/22 |
| Andre Pallante | Monk's Café | DROP | to FA | 7:43 pm, 8/5/22 |