| Player | Team | Action | Details | |
|---|---|---|---|---|
| Michael Burrows | Monk's Café | DROP | to FA | 1:52 am, 8/14/22 |
| Jorge Alfaro | Monk's Café | DROP | to FA | 1:36 am, 8/14/22 |
| Connor Joe | Monk's Café | DROP | to FA | 1:35 am, 8/14/22 |
| Yadier Molina | Undead Rabbits | DROP | to FA | 10:23 am, 8/13/22 |
| Dakota Hudson | Geckos | DROP | to FA | 8:55 pm, 8/12/22 |
| Erik Swanson | Undead Rabbits | DROP | to FA | 2:55 pm, 8/12/22 |
| Frank Schwindel | The Red Barons | DROP | to FA | 9:38 am, 8/12/22 |
| Yerry de los Santos | The Red Barons | DROP | to FA | 9:36 am, 8/12/22 |
| Rich Hill | Supreme Clientele | DROP | to FA | 10:30 pm, 8/11/22 |
| Adrian Houser | Supreme Clientele | DROP | to FA | 10:30 pm, 8/11/22 |
| Andre Pallante | Ye Olde Tom Toolshed | DROP | to FA | 8:56 pm, 8/10/22 |
| Garrett Cooper | Cowboys From Hell | DROP | to FA | 8:08 pm, 8/10/22 |
| Hans Crouse | Ye Olde Tom Toolshed | DROP | to FA | 3:29 pm, 8/10/22 |
| A.J. Minter | Ye Olde Tom Toolshed | DROP | to FA | 9:28 am, 8/10/22 |
| Bryce Elder | Monk's Café | DROP | to FA | 7:12 am, 8/10/22 |
| Reynaldo Lopez | Monk's Café | DROP | to FA | 6:34 am, 8/10/22 |
| Aeverson Arteaga | Monk's Café | DROP | to FA | 6:33 am, 8/10/22 |
| Jaison Chourio | Monk's Café | DROP | to FA | 6:30 am, 8/10/22 |
| Nelson Velasquez | Chinballs | DROP | to FA | 10:15 pm, 8/9/22 |
| Hao Yu Lee | The Red Barons | DROP | to FA | 9:59 pm, 8/9/22 |
| J.D. Davis | The Red Barons | DROP | to FA | 7:00 pm, 8/9/22 |
| Evan Longoria | Chinballs | DROP | to FA | 1:09 pm, 8/9/22 |
| Lou Trivino | Ye Olde Tom Toolshed | DROP | to FA | 11:41 am, 8/9/22 |
| Brett Martin | Ye Olde Tom Toolshed | DROP | to FA | 11:41 am, 8/9/22 |
| Royber Salinas | Monk's Café | DROP | to FA | 11:26 pm, 8/8/22 |