| Player | Team | Action | Details | |
|---|---|---|---|---|
| Starling Marte | Purple Cobras | DROP | to FA | 3:54 pm, 2/20/22 |
| Austin Hays | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| A.J. Pollock | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Charlie Blackmon | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Trea Turner | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Jose Altuve | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Jake Cronenworth | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Brandon Lowe | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Frank Schwindel | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Andy Ibanez | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Tejay Antone | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Yonny Chirinos | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Andres Munoz | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Connor Joe | Purple Cobras | DROP | to FA | 3:53 pm, 2/20/22 |
| Jake McGee | Purple Cobras | DROP | to FA | 3:52 pm, 2/20/22 |
| Andre Jackson | Purple Cobras | DROP | to FA | 3:52 pm, 2/20/22 |
| Samad Taylor | Purple Cobras | DROP | to FA | 3:52 pm, 2/20/22 |
| Yuli Gurriel | Purple Cobras | DROP | to FA | 3:52 pm, 2/20/22 |
| Elias Diaz | Purple Cobras | DROP | to FA | 3:52 pm, 2/20/22 |
| Pavin Smith | Supreme Clientele | DROP | to FA | 2:11 pm, 2/8/22 |
| Erick Pena | The Red Barons | DROP | to FA | 11:03 pm, 1/27/22 |
| Micker Adolfo | The Red Barons | DROP | to FA | 11:03 pm, 1/27/22 |
| Michael Baumann | The Red Barons | DROP | to FA | 11:03 pm, 1/27/22 |
| Brice Turang | Chinballs | DROP | to FA | 11:59 pm, 1/20/22 |
| Hudson Head | Chinballs | DROP | to FA | 11:59 pm, 1/20/22 |