| Player | Team | Action | Details | |
|---|---|---|---|---|
| Eli Morgan | Cowboys From Hell | DROP | to FA | 4:44 pm, 6/6/21 |
| David Fletcher | Geckos | DROP | to FA | 1:42 pm, 6/6/21 |
| Billy Hamilton | Bullet Club | DROP | to FA | 1:41 pm, 6/6/21 |
| Harold Ramirez | The Bluth Company | DROP | to FA | 1:48 pm, 6/5/21 |
| Gavin Sheets | The Bluth Company | DROP | to FA | 1:47 pm, 6/5/21 |
| Tyler Ivey | Purple Cobras | DROP | to FA | 1:21 pm, 6/5/21 |
| Niko Goodrum | Shaolin Schmeckles | DROP | to FA | 12:10 pm, 6/5/21 |
| Connor Seabold | Purple Cobras | DROP | to FA | 5:47 am, 6/5/21 |
| Jhonkensy Noel | The Bluth Company | DROP | to FA | 7:25 pm, 6/4/21 |
| Wilmer Flores | Shaolin Schmeckles | DROP | to FA | 6:53 pm, 6/4/21 |
| Thairo Estrada | The Bluth Company | DROP | to FA | 11:03 pm, 6/3/21 |
| Jose Rojas | Shaolin Schmeckles | DROP | to FA | 9:25 pm, 6/3/21 |
| Asdrubal Cabrera | Purple Cobras | DROP | to FA | 6:50 pm, 6/3/21 |
| Willians Astudillo | Shaolin Schmeckles | DROP | to FA | 6:38 pm, 6/3/21 |
| Garrett Cooper | Bullet Club | DROP | to FA | 3:07 pm, 6/3/21 |
| Drew Smyly | Bullet Club | DROP | to FA | 12:10 pm, 6/3/21 |
| Demarcus Evans | Chinballs | DROP | to FA | 10:43 am, 6/3/21 |
| Matt Beaty | Purple Cobras | DROP | to FA | 7:01 am, 6/3/21 |
| Kyle Freeland | Supreme Clientele | DROP | to FA | 6:58 pm, 6/2/21 |
| J.A. Happ | Supreme Clientele | DROP | to FA | 6:58 pm, 6/2/21 |
| Eric Lauer | Supreme Clientele | DROP | to FA | 6:58 pm, 6/2/21 |
| Vincent Velasquez | Supreme Clientele | DROP | to FA | 6:58 pm, 6/2/21 |
| Alex Colome | Shaolin Schmeckles | DROP | to FA | 6:47 pm, 6/2/21 |
| Yan Gomes | Purple Cobras | DROP | to FA | 5:06 pm, 6/2/21 |
| Hunter Brown | The Red Barons | DROP | to FA | 12:28 pm, 6/2/21 |