| Player | Team | Action | Details | |
|---|---|---|---|---|
| Ivan Herrera | The Bluth Company | DROP | to FA | 7:17 pm, 5/29/21 |
| Miguel Rojas | Shaolin Schmeckles | DROP | to FA | 11:49 am, 5/29/21 |
| Juan Lagares | Geckos | DROP | to FA | 11:01 am, 5/29/21 |
| Yandy Diaz | Geckos | DROP | to FA | 11:01 am, 5/29/21 |
| Cory Abbott | Purple Cobras | DROP | to FA | 9:33 am, 5/28/21 |
| Will Craig | Shaolin Schmeckles | DROP | to FA | 8:08 am, 5/28/21 |
| Will Crowe | Cowboys From Hell | DROP | to FA | 7:19 pm, 5/27/21 |
| Adam Eaton | Geckos | DROP | to FA | 6:45 pm, 5/27/21 |
| Zack Thompson | Jon Voight's Car | DROP | to FA | 5:09 pm, 5/27/21 |
| Tyler Duffey | Nixon's Nasty Ninjas | DROP | to FA | 9:17 am, 5/27/21 |
| Stefan Crichton | Shaolin Schmeckles | DROP | to FA | 8:37 am, 5/27/21 |
| Chris Owings | Purple Cobras | DROP | to FA | 8:12 pm, 5/26/21 |
| Jordan Luplow | Shaolin Schmeckles | DROP | to FA | 4:44 pm, 5/26/21 |
| Greg Holland | Scranton Yankees | DROP | to FA | 3:40 pm, 5/26/21 |
| Willians Astudillo | Scranton Yankees | DROP | to FA | 3:39 pm, 5/26/21 |
| Lyon Richardson | The Bluth Company | DROP | to FA | 11:53 am, 5/26/21 |
| Carmen Mlodzinski | The Bluth Company | DROP | to FA | 10:44 am, 5/26/21 |
| Brandon Lewis | Geckos | DROP | to FA | 10:33 am, 5/26/21 |
| Ryne Stanek | Chinballs | DROP | to FA | 10:02 am, 5/26/21 |
| Sam Carlson | The Red Barons | DROP | to FA | 8:09 am, 5/26/21 |
| Scott Kazmir | The Bluth Company | DROP | to FA | 6:43 pm, 5/25/21 |
| Niko Goodrum | Shaolin Schmeckles | DROP | to FA | 6:36 pm, 5/25/21 |
| David Fletcher | Supreme Clientele | DROP | to FA | 5:07 pm, 5/25/21 |
| Kyle Higashioka | Geckos | DROP | to FA | 5:01 pm, 5/25/21 |
| Yadiel Hernandez | The Bluth Company | DROP | to FA | 4:59 pm, 5/25/21 |