| Player | Team | Action | Details | |
|---|---|---|---|---|
| Yohander Mendez | The Bluth Company | DROP | to FA | 11:39 pm, 5/11/16 |
| Kyle Freeland | Supreme Clientele | DROP | to FA | 11:37 pm, 5/11/16 |
| Ricky Nolasco | The Bluth Company | DROP | to FA | 10:38 pm, 5/11/16 |
| Jayson Werth | Purple Cobras | DROP | to FA | 10:10 pm, 5/11/16 |
| Ivan Nova | Geckos | DROP | to FA | 9:21 pm, 5/11/16 |
| Hyun-Soo Kim | Geckos | DROP | to FA | 9:20 pm, 5/11/16 |
| Chris Young | Jon Voight's Car | DROP | to FA | 8:13 pm, 5/11/16 |
| Chase Anderson | Jon Voight's Car | DROP | to FA | 8:12 pm, 5/11/16 |
| Seth Smith | Supreme Clientele | DROP | to FA | 11:48 am, 5/11/16 |
| Justin Smoak | Supreme Clientele | DROP | to FA | 11:45 am, 5/11/16 |
| Anderson Franco | Young Tommy Toolsheds | DROP | to FA | 3:35 pm, 5/10/16 |
| Mike Wright | Supreme Clientele | DROP | to FA | 11:35 pm, 5/9/16 |
| Jesus Montero | Geckos | DROP | to FA | 5:53 pm, 5/9/16 |
| Silvino Bracho | Nixon's Nasty Ninjas | DROP | to FA | 2:42 pm, 5/9/16 |
| Geovany Soto | Cowboys From Hell | DROP | to FA | 1:53 pm, 5/9/16 |
| Fernando Salas | Cowboys From Hell | DROP | to FA | 1:53 pm, 5/9/16 |
| Juan Hillman | Cowboys From Hell | DROP | to FA | 1:53 pm, 5/9/16 |
| Nick Vincent | Chinballs | DROP | to FA | 12:38 pm, 5/9/16 |
| Daniel Palka | Young Tommy Toolsheds | DROP | to FA | 10:09 am, 5/9/16 |
| Nick Burdi | Young Tommy Toolsheds | DROP | to FA | 10:08 am, 5/9/16 |
| Michael Brantley | Young Tommy Toolsheds | DROP | to FA | 8:57 am, 5/9/16 |
| Harold Ramirez | Scranton Yankees | DROP | to FA | 8:10 am, 5/9/16 |
| Tommy Milone | Dead Rabbits | DROP | to FA | 11:36 pm, 5/8/16 |
| Ender Inciarte | Dead Rabbits | DROP | to FA | 11:36 pm, 5/8/16 |
| Brian Johnson | Supreme Clientele | DROP | to FA | 10:11 pm, 5/8/16 |