| Player | Team | Action | Details | |
|---|---|---|---|---|
| Marwin Gonzalez | The Bluth Company | DROP | to FA | 12:54 am, 5/6/16 |
| Chase Anderson | Geckos | DROP | to FA | 12:40 am, 5/6/16 |
| Erik Johnson | Cowboys From Hell | DROP | to FA | 9:48 pm, 5/5/16 |
| Victor Alcantara | Shaolin Schmeckles | DROP | to FA | 8:37 pm, 5/5/16 |
| Jered Weaver | Banana Hammock | DROP | to FA | 7:26 pm, 5/5/16 |
| Blake Treinen | Supreme Clientele | DROP | to FA | 10:44 am, 5/5/16 |
| Justin Bour | Purple Cobras | DROP | to FA | 6:46 am, 5/5/16 |
| Adam Morgan | The Bluth Company | DROP | to FA | 11:56 pm, 5/4/16 |
| Jake Peavy | The Bluth Company | DROP | to FA | 2:08 pm, 5/4/16 |
| Daniel Mengden | The Bluth Company | DROP | to FA | 11:47 am, 5/4/16 |
| Joey Rickard | Purple Cobras | DROP | to FA | 10:28 am, 5/4/16 |
| Addison Reed | Kimble's Kids | DROP | to FA | 10:06 am, 5/4/16 |
| Robbie Erlin | Purple Cobras | DROP | to FA | 9:20 am, 5/4/16 |
| Steve Pearce | Supreme Clientele | DROP | to FA | 3:00 am, 5/4/16 |
| Brian Johnson | Supreme Clientele | DROP | to FA | 2:58 am, 5/4/16 |
| Chris Iannetta | Cowboys From Hell | DROP | to FA | 11:06 pm, 5/3/16 |
| John Danks | Scranton Yankees | DROP | to FA | 11:04 pm, 5/3/16 |
| Jeremy Hazelbaker | Supreme Clientele | DROP | to FA | 10:35 pm, 5/3/16 |
| Ross Ohlendorf | Supreme Clientele | DROP | to FA | 10:23 pm, 5/3/16 |
| Nick Markakis | Scranton Yankees | DROP | to FA | 4:58 pm, 5/3/16 |
| Fernando Salas | Cowboys From Hell | DROP | to FA | 4:53 pm, 5/3/16 |
| Justin Wilson | Cowboys From Hell | DROP | to FA | 4:53 pm, 5/3/16 |
| Angel Perdomo | The Bluth Company | DROP | to FA | 4:33 pm, 5/3/16 |
| R.A. Dickey | Supreme Clientele | DROP | to FA | 3:24 pm, 5/3/16 |
| Jose Ramirez | Chinballs | DROP | to FA | 3:11 pm, 5/3/16 |