| Player | Team | Action | Details | |
|---|---|---|---|---|
| Kevin Gausman | Kimble's Kids | ADD | to MLB | 4:20 pm, 2/20/22 |
| Tyler Mahle | Kimble's Kids | ADD | to MLB | 4:20 pm, 2/20/22 |
| Jose Altuve | Kimble's Kids | ADD | to MLB | 4:08 pm, 2/20/22 |
| Luis Castillo | Kimble's Kids | ADD | to MLB | 4:08 pm, 2/20/22 |
| Sean Manaea | Kimble's Kids | ADD | to MLB | 4:08 pm, 2/20/22 |
| Spencer Torkelson | Kimble's Kids | ADD | to AA | 4:08 pm, 2/20/22 |
| Lucas Giolito | Kimble's Kids | ADD | to MLB | 4:08 pm, 2/20/22 |
| Trea Turner | Kimble's Kids | ADD | to MLB | 4:08 pm, 2/20/22 |
| Ian Seymour | Chinballs | ADD | to MLB | 2:09 am, 1/21/22 |
| Alex Canario | Undead Rabbits | ADD | to AAA | 1:19 am, 1/20/22 |
| Evan Longoria | Undead Rabbits | ADD | to MLB | 1:07 pm, 1/19/22 |
| Brett Anderson | Bridge Four | ADD | to MLB | 4:58 pm, 1/10/22 |
| Yusmeiro Petit | Bridge Four | ADD | to MLB | 4:57 pm, 1/10/22 |
| Jon Lester | Bridge Four | ADD | to MLB | 4:57 pm, 1/10/22 |
| David Peralta | Bridge Four | ADD | to MLB | 4:56 pm, 1/10/22 |
| Yan Gomes | Bridge Four | ADD | to MLB | 4:56 pm, 1/10/22 |
| Brad Miller | Bridge Four | ADD | to MLB | 4:53 pm, 1/10/22 |
| Asdrubal Cabrera | Bridge Four | ADD | to MLB | 4:52 pm, 1/10/22 |
| Josh Rogers | Undead Rabbits | ADD | to MLB | 12:42 pm, 10/14/21 |
| Matt Wisler | The Bluth Company | ADD | to MLB | 12:00 am, 10/8/21 |
| Adrian Houser | Supreme Clientele | ADD | to MLB | 3:30 pm, 10/4/21 |
| Nick Pivetta | Supreme Clientele | ADD | to MLB | 3:30 pm, 10/4/21 |
| Yandy Diaz | The Red Barons | ADD | to MLB | 2:18 pm, 10/3/21 |
| Darin Ruf | The Bluth Company | ADD | to MLB | 12:32 pm, 10/2/21 |
| Rowan Wick | Ye Olde Tom Toolshed | ADD | to MLB | 9:51 am, 10/1/21 |