| Player | Team | Action | Details | |
|---|---|---|---|---|
| Chad Pinder | Chinballs | ADD | to MLB | 11:12 am, 5/4/22 |
| Keegan Thompson | Undead Rabbits | ADD | to MLB | 9:48 am, 5/4/22 |
| Drew Romo | The Bluth Company | ADD | to AAA | 9:47 am, 5/4/22 |
| Jose Butto | Geckos | ADD | to AAA | 9:46 am, 5/4/22 |
| Edward Olivares | Undead Rabbits | ADD | to MLB | 7:02 am, 5/4/22 |
| Brandon Drury | The Red Barons | ADD | to MLB | 5:25 pm, 5/3/22 |
| Alex Faedo | Cowboys From Hell | ADD | to MLB | 5:13 pm, 5/3/22 |
| Andy Ibanez | The Red Barons | ADD | to MLB | 3:48 pm, 5/3/22 |
| Jon Berti | Bullet Club | ADD | to MLB | 2:20 pm, 5/3/22 |
| Duane Underwood | Undead Rabbits | ADD | to AAA | 8:33 am, 5/3/22 |
| Trevor Stephan | The Bluth Company | ADD | to MLB | 6:45 am, 5/3/22 |
| Huascar Ynoa | The Bluth Company | ADD | to NA | 6:44 am, 5/3/22 |
| Yadiel Hernandez | The Bluth Company | ADD | to MLB | 11:46 pm, 5/2/22 |
| Ross Stripling | The Bluth Company | ADD | to MLB | 11:44 pm, 5/2/22 |
| Jose Trevino | Monk's Café | ADD | to MLB | 5:04 pm, 5/2/22 |
| Trey Cabbage | Monk's Café | ADD | to AAA | 3:47 pm, 5/2/22 |
| Rich Hill | Supreme Clientele | ADD | to MLB | 3:35 pm, 5/2/22 |
| Peyton Battenfield | Monk's Café | ADD | to AAA | 3:34 pm, 5/2/22 |
| Anthony Garcia | Monk's Café | ADD | to AA | 3:23 pm, 5/2/22 |
| Dominic Smith | Geckos | ADD | to MLB | 10:05 am, 5/2/22 |
| Kendall Graveman | Ye Olde Tom Toolshed | ADD | to MLB | 9:24 am, 5/2/22 |
| Santiago Espinal | Ye Olde Tom Toolshed | ADD | to MLB | 9:23 am, 5/2/22 |
| Jalen Beeks | The Red Barons | ADD | to MLB | 8:46 am, 5/2/22 |
| Kyle Higashioka | Monk's Café | ADD | to MLB | 1:47 pm, 5/1/22 |
| Travis Demeritte | Cowboys From Hell | ADD | to MLB | 9:31 am, 5/1/22 |