| Player | Team | Action | Details | |
|---|---|---|---|---|
| Jordan Lyles | Supreme Clientele | ADD | to MLB | 2:36 pm, 5/29/21 |
| Evan Longoria | Supreme Clientele | ADD | to MLB | 2:36 pm, 5/29/21 |
| Lucas Sims | Shaolin Schmeckles | ADD | to MLB | 11:50 am, 5/29/21 |
| Niko Goodrum | Shaolin Schmeckles | ADD | to MLB | 11:50 am, 5/29/21 |
| David Fletcher | Geckos | ADD | to MLB | 11:02 am, 5/29/21 |
| Billy McKinney | Geckos | ADD | to MLB | 11:02 am, 5/29/21 |
| Carmen Mlodzinski | Purple Cobras | ADD | to A | 10:44 am, 5/28/21 |
| Edmundo Sosa | Shaolin Schmeckles | ADD | to MLB | 8:09 am, 5/28/21 |
| Eli Morgan | Cowboys From Hell | ADD | to MLB | 7:19 pm, 5/27/21 |
| Maikol Escotto | Jon Voight's Car | ADD | to AAA | 7:13 pm, 5/27/21 |
| Juan Lagares | Geckos | ADD | to MLB | 6:45 pm, 5/27/21 |
| Scott Kazmir | Purple Cobras | ADD | to MLB | 6:44 pm, 5/27/21 |
| Gregory Soto | Nixon's Nasty Ninjas | ADD | to MLB | 9:17 am, 5/27/21 |
| Keynan Middleton | Shaolin Schmeckles | ADD | to MLB | 8:37 am, 5/27/21 |
| Will Craig | Shaolin Schmeckles | ADD | to MLB | 6:23 pm, 5/26/21 |
| Ivan Herrera | The Bluth Company | ADD | to A | 11:53 am, 5/26/21 |
| Demarcus Evans | Chinballs | ADD | to AAA | 10:45 am, 5/26/21 |
| Taj Bradley | The Bluth Company | ADD | to A | 10:44 am, 5/26/21 |
| Joshua Mears | Geckos | ADD | to A | 10:33 am, 5/26/21 |
| Jonathan Loaisiga | Chinballs | ADD | to MLB | 10:02 am, 5/26/21 |
| Justin Upton | The Red Barons | ADD | to MLB | 8:10 am, 5/26/21 |
| Jordan Luplow | Shaolin Schmeckles | ADD | to MLB | 6:38 pm, 5/25/21 |
| Vladimir Gutierrez | The Bluth Company | ADD | to AAA | 6:36 pm, 5/25/21 |
| Caleb Kilian | The Bluth Company | ADD | to AAA | 4:59 pm, 5/25/21 |
| Thairo Estrada | The Bluth Company | ADD | to AAA | 2:22 pm, 5/25/21 |