| Player | Team | Action | Details | |
|---|---|---|---|---|
| Wilmer Flores | Shaolin Schmeckles | ADD | to MLB | 11:09 pm, 5/10/21 |
| Brice Turang | Chinballs | ADD | to AAA | 10:47 pm, 5/10/21 |
| Marwin Gonzalez | Chinballs | ADD | to MLB | 10:43 pm, 5/10/21 |
| Lyon Richardson | The Bluth Company | ADD | to A | 12:15 pm, 5/10/21 |
| Adam Frazier | Cowboys From Hell | ADD | to MLB | 10:10 am, 5/10/21 |
| Freddy Galvis | Cowboys From Hell | ADD | to MLB | 9:55 am, 5/10/21 |
| Rowdy Tellez | The Red Barons | ADD | to MLB | 9:09 am, 5/10/21 |
| Carmen Mlodzinski | The Bluth Company | ADD | to AAA | 11:32 pm, 5/9/21 |
| Yadiel Hernandez | The Bluth Company | ADD | to AAA | 11:09 pm, 5/9/21 |
| Drew Strotman | The Bluth Company | ADD | to AAA | 8:43 pm, 5/9/21 |
| Pablo Sandoval | Shaolin Schmeckles | ADD | to MLB | 8:08 pm, 5/9/21 |
| Nick Gordon | Bridge Four | ADD | to MLB | 4:06 pm, 5/9/21 |
| Yandy Diaz | Geckos | ADD | to MLB | 3:41 pm, 5/9/21 |
| Trevor Hauver | Shaolin Schmeckles | ADD | to AA | 3:38 pm, 5/9/21 |
| Hyeon-Jong Yang | Shaolin Schmeckles | ADD | to MLB | 3:37 pm, 5/9/21 |
| Christopher Morel | Purple Cobras | ADD | to AA | 3:34 pm, 5/9/21 |
| Mark Appel | Undead Rabbits | ADD | to AA | 2:02 pm, 5/9/21 |
| Ryan Helsley | Cowboys From Hell | ADD | to MLB | 1:40 pm, 5/9/21 |
| A.J. Minter | Cowboys From Hell | ADD | to MLB | 1:40 pm, 5/9/21 |
| Chase Strumpf | Geckos | ADD | to AAA | 2:30 am, 5/9/21 |
| Terrin Vavra | Geckos | ADD | to AA | 2:21 am, 5/9/21 |
| Franchy Cordero | Undead Rabbits | ADD | to MLB | 9:38 pm, 5/8/21 |
| Brice Turang | The Bluth Company | ADD | to AAA | 8:01 pm, 5/8/21 |
| Riley Smith | Bridge Four | ADD | to MLB | 6:37 pm, 5/8/21 |
| Codi Heuer | Bridge Four | ADD | to MLB | 6:36 pm, 5/8/21 |