| Player | Team | Action | Details | |
|---|---|---|---|---|
| Angel Martinez | Bullet Club | DROP | to FA | 1:59 am, 4/8/22 |
| Justin Upton | Monk's Café | DROP | to FA | 2:05 pm, 4/7/22 |
| Brice Turang | The Bluth Company | DROP | to FA | 9:21 am, 4/7/22 |
| Korey Lee | The Bluth Company | DROP | to FA | 10:20 pm, 4/6/22 |
| Jordyn Adams | Bullet Club | DROP | to FA | 5:02 pm, 4/6/22 |
| Joshua Baez | The Red Barons | DROP | to FA | 4:21 pm, 4/6/22 |
| Gio Urshela | The Red Barons | DROP | to FA | 9:33 am, 4/6/22 |
| Nick Bitsko | Scranton Yankees | DROP | to FA | 6:59 am, 4/6/22 |
| Dax Fulton | The Bluth Company | DROP | to FA | 10:31 pm, 4/5/22 |
| Max Stassi | Geckos | DROP | to FA | 10:18 pm, 4/5/22 |
| Connor Seabold | Monk's Café | DROP | to FA | 8:29 pm, 4/5/22 |
| Bryan De La Cruz | Monk's Café | DROP | to FA | 7:28 pm, 4/5/22 |
| Touki Toussaint | Monk's Café | DROP | to FA | 7:28 pm, 4/5/22 |
| Angel Zerpa | Cowboys From Hell | DROP | to FA | 12:03 pm, 4/5/22 |
| Amir Garrett | Undead Rabbits | DROP | to FA | 11:21 am, 4/5/22 |
| Julian Merryweather | Undead Rabbits | DROP | to FA | 11:06 am, 4/5/22 |
| Ethan Elliott | Undead Rabbits | DROP | to FA | 10:39 am, 4/5/22 |
| Eric Haase | Undead Rabbits | DROP | to FA | 10:37 am, 4/5/22 |
| Ross Stripling | Ye Olde Tom Toolshed | DROP | to FA | 9:36 am, 4/5/22 |
| Evan Longoria | Undead Rabbits | DROP | to FA | 11:31 pm, 4/4/22 |
| Joakim Soria | Bridge Four | DROP | to FA | 8:53 pm, 4/4/22 |
| Mitchell Parker | Jon Voight's Car | DROP | to FA | 11:55 am, 3/26/22 |
| Sherten Apostel | Jon Voight's Car | DROP | to FA | 11:54 am, 3/26/22 |
| Chris Martin | Jon Voight's Car | DROP | to FA | 11:46 am, 3/26/22 |
| Codi Heuer | Bridge Four | DROP | to FA | 9:19 pm, 3/25/22 |