| Player | Team | Action | Details | |
|---|---|---|---|---|
| Michael King | Cowboys From Hell | DROP | to FA | 4:52 pm, 3/24/22 |
| Slade Cecconi | Ye Olde Tom Toolshed | DROP | to FA | 3:40 pm, 3/24/22 |
| Matthew Frazier | The Bluth Company | DROP | to FA | 9:27 pm, 3/23/22 |
| Aeverson Arteaga | The Bluth Company | DROP | to FA | 9:27 pm, 3/23/22 |
| Joey Estes | Shaolin Schmeckles | DROP | to FA | 2:35 pm, 3/23/22 |
| Edward Olivares | Shaolin Schmeckles | DROP | to FA | 2:32 pm, 3/23/22 |
| Brad Keller | Shaolin Schmeckles | DROP | to FA | 2:32 pm, 3/23/22 |
| Noah Song | Shaolin Schmeckles | DROP | to FA | 2:27 pm, 3/23/22 |
| Sam Huff | Shaolin Schmeckles | DROP | to FA | 2:18 pm, 3/23/22 |
| Carlos Estevez | Shaolin Schmeckles | DROP | to FA | 2:16 pm, 3/23/22 |
| Buddy Kennedy | Shaolin Schmeckles | DROP | to FA | 2:14 pm, 3/23/22 |
| Kyle Farmer | Shaolin Schmeckles | DROP | to FA | 2:13 pm, 3/23/22 |
| Justin Steele | Shaolin Schmeckles | DROP | to FA | 2:04 pm, 3/23/22 |
| Trevor Rosenthal | Shaolin Schmeckles | DROP | to FA | 1:57 pm, 3/23/22 |
| Edwin Rios | Shaolin Schmeckles | DROP | to FA | 1:55 pm, 3/23/22 |
| Jose Leclerc | Shaolin Schmeckles | DROP | to FA | 1:52 pm, 3/23/22 |
| Dillon Peters | Shaolin Schmeckles | DROP | to FA | 1:50 pm, 3/23/22 |
| Tyler Clippard | Shaolin Schmeckles | DROP | to FA | 1:48 pm, 3/23/22 |
| Josh Fleming | Shaolin Schmeckles | DROP | to FA | 1:45 pm, 3/23/22 |
| Luke Weaver | Supreme Clientele | DROP | to FA | 12:55 am, 3/23/22 |
| Ryne Nelson | Supreme Clientele | DROP | to FA | 12:52 am, 3/23/22 |
| Adrian Houser | Supreme Clientele | DROP | to FA | 12:30 am, 3/23/22 |
| Adam Engel | Ye Olde Tom Toolshed | DROP | to FA | 12:09 pm, 3/22/22 |
| Ryan Vilade | Ye Olde Tom Toolshed | DROP | to FA | 12:05 pm, 3/22/22 |
| Jake McCarthy | Ye Olde Tom Toolshed | DROP | to FA | 12:04 pm, 3/22/22 |