| Player | Team | Action | Details | |
|---|---|---|---|---|
| Bryce Ball | The Bluth Company | DROP | to FA | 11:32 am, 6/1/22 |
| Jordan Balazovic | Chinballs | DROP | to FA | 11:01 am, 6/1/22 |
| Emmanuel Rivera | Chinballs | DROP | to FA | 10:45 am, 6/1/22 |
| Harold Ramirez | Chinballs | DROP | to FA | 10:45 am, 6/1/22 |
| Sam Hentges | The Red Barons | DROP | to FA | 7:59 am, 6/1/22 |
| Ji-Hwan Bae | The Bluth Company | DROP | to FA | 1:12 am, 6/1/22 |
| Grant McCray | The Bluth Company | DROP | to FA | 1:10 am, 6/1/22 |
| Diego Castillo | Cowboys From Hell | DROP | to FA | 6:50 am, 5/31/22 |
| Erick Fedde | Bullet Club | DROP | to FA | 9:22 pm, 5/30/22 |
| Taylor Trammell | Scranton Yankees | DROP | to FA | 9:13 pm, 5/30/22 |
| Francisco Mejia | Scranton Yankees | DROP | to FA | 9:10 pm, 5/30/22 |
| Owen White | The Bluth Company | DROP | to FA | 12:15 pm, 5/30/22 |
| Michael King | The Bluth Company | DROP | to FA | 11:00 am, 5/30/22 |
| Dylan Floro | Cowboys From Hell | DROP | to FA | 8:40 am, 5/30/22 |
| Isiah Kiner-Falefah | Bullet Club | DROP | to FA | 6:54 am, 5/30/22 |
| Kyle Freeland | Chinballs | DROP | to FA | 3:26 am, 5/30/22 |
| Cody Poteet | Chinballs | DROP | to FA | 2:47 am, 5/30/22 |
| Aaron Sabato | The Red Barons | DROP | to FA | 12:25 am, 5/30/22 |
| J.T. Ginn | The Red Barons | DROP | to FA | 11:52 pm, 5/29/22 |
| Kole Calhoun | Cowboys From Hell | DROP | to FA | 8:05 pm, 5/29/22 |
| Bobby Dalbec | Cowboys From Hell | DROP | to FA | 7:56 pm, 5/29/22 |
| Jordan Balazovic | Supreme Clientele | DROP | to FA | 11:46 am, 5/29/22 |
| Brian Anderson | The Red Barons | DROP | to FA | 4:16 am, 5/29/22 |
| Jeimer Candelario | The Red Barons | DROP | to FA | 4:08 am, 5/29/22 |
| Matthew Strahm | The Red Barons | DROP | to FA | 4:08 am, 5/29/22 |