| Player | Team | Action | Details | |
|---|---|---|---|---|
| Andrew McCutchen | Shaolin Schmeckles | DROP | to FA | 11:10 pm, 4/27/21 |
| Wilmer Flores | Geckos | DROP | to FA | 8:10 pm, 4/27/21 |
| Corey Ray | Shaolin Schmeckles | DROP | to FA | 6:23 pm, 4/27/21 |
| Mike Fiers | Shaolin Schmeckles | DROP | to FA | 3:13 pm, 4/27/21 |
| Garrett Cooper | Chinballs | DROP | to FA | 10:42 am, 4/27/21 |
| Jordan Romero | Chinballs | DROP | to FA | 10:42 am, 4/27/21 |
| Nick Neidert | Chinballs | DROP | to FA | 10:42 am, 4/27/21 |
| Franchy Cordero | Chinballs | DROP | to FA | 10:41 am, 4/27/21 |
| Dom Nunez | Undead Rabbits | DROP | to FA | 12:06 am, 4/27/21 |
| Martin Perez | Undead Rabbits | DROP | to FA | 11:42 pm, 4/26/21 |
| Keegan Akin | Supreme Clientele | DROP | to FA | 5:36 pm, 4/26/21 |
| Emilio Pagán | Cowboys From Hell | DROP | to FA | 2:22 pm, 4/26/21 |
| Randy Dobnak | Cowboys From Hell | DROP | to FA | 2:19 pm, 4/26/21 |
| Corey Dickerson | Cowboys From Hell | DROP | to FA | 2:19 pm, 4/26/21 |
| Mike Brosseau | Cowboys From Hell | DROP | to FA | 2:19 pm, 4/26/21 |
| Chad Kuhl | Cowboys From Hell | DROP | to FA | 2:18 pm, 4/26/21 |
| Logan S. Allen | The Red Barons | DROP | to FA | 1:31 pm, 4/26/21 |
| Sam Hilliard | Bullet Club | DROP | to FA | 12:59 pm, 4/26/21 |
| Johan Rojas | The Bluth Company | DROP | to FA | 12:29 pm, 4/26/21 |
| Willi Castro | Ye Olde Tom Toolshed | DROP | to FA | 10:42 am, 4/26/21 |
| Joey Lucchesi | Supreme Clientele | DROP | to FA | 10:27 am, 4/26/21 |
| Jose De Leon | Supreme Clientele | DROP | to FA | 10:27 am, 4/26/21 |
| Travis Shaw | Purple Cobras | DROP | to FA | 10:24 am, 4/26/21 |
| Stefan Crichton | Shaolin Schmeckles | DROP | to FA | 3:36 pm, 4/25/21 |
| Adam Frazier | Geckos | DROP | to FA | 2:20 pm, 4/25/21 |